Literature DB >> 7562892

Managing hypertension in general practice: can we do better?

J Hosie1, I Wiklund.   

Abstract

Two surveys of hypertension treatment in Europe have revealed major differences between doctor perception, patient belief and the reality of BP control. The first survey (part of the Cardiomonitor Study) investigated 23,339 cardiovascular patients treated by 1471 doctors in Italy, Spain, France, the UK and Germany. The second survey researched attitudes to treatment among 301 general practitioners and 300 patients in Italy, France and the UK. Cardiomonitor revealed that hypertension was poorly controlled, with only 37% of patients achieving target BP. In contrast, the second survey revealed that doctors believed that target BP was reached in the majority (76%) of their treated patients with hypertension, while an even higher percentage of patients (95%) believed their BP to be well controlled. There were significant discrepancies in the perceived reasons for treatment failure between doctors and patients. Most doctors considered poor compliance with therapy to be the main reason for failure to achieve target BP. In contrast, most patients reported good compliance, blaming poor efficacy or side-effects for treatment failure. Objective studies suggest that compliance is lower than patients report and can be reduced by factors that affect quality of life, such as side-effects of treatment, complex dosing regimens, changes in therapy and concern about poorly controlled disease. This argues for effective, well-tolerated antihypertensive drugs that can be taken once daily, enabling quality of life to be maintained throughout treatment.

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Year:  1995        PMID: 7562892

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN: 0950-9240            Impact factor:   3.012


  17 in total

Review 1.  Treating to protect: current cardiovascular treatment approaches and remaining needs.

Authors:  Michael Böhm; Christian Werner; Anne Jakobsen; Jose Heroys; Ann Ralph; Tomas Rees; Michael Shaw
Journal:  Medscape J Med       Date:  2008-03-26

2.  Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up.

Authors:  F Fici; G Seravalle; N Koylan; I Nalbantgil; N Cagla; Y Korkut; F Quarti-Trevano; W Makel; G Grassi
Journal:  High Blood Press Cardiovasc Prev       Date:  2017-05-11

Review 3.  Rationale for fixed-dose combinations in the treatment of hypertension: the cycle repeats.

Authors:  Domenic A Sica
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 4.  Desirable therapeutic characteristics of an optimal antihypertensive agent.

Authors:  Lisa Mustone Alexander
Journal:  Drugs       Date:  2006       Impact factor: 9.546

Review 5.  The relationship between quality of life and adherence to treatment.

Authors:  M I Nunes
Journal:  Curr Hypertens Rep       Date:  2001-12       Impact factor: 5.369

Review 6.  Felodipine/metoprolol: a review of the fixed dose controlled release formulation in the management of essential hypertension.

Authors:  M Haria; G L Plosker; A Markham
Journal:  Drugs       Date:  2000-01       Impact factor: 9.546

7.  Treated hypertensives with good medication compliance are still in a state of uncontrolled blood pressure in the Japanese elderly.

Authors:  Junko Okuno; Shigeo Tomura; Hisako Yanagi
Journal:  Environ Health Prev Med       Date:  2002-11       Impact factor: 3.674

Review 8.  Fixed-dose combination enalapril/nitrendipine: a review of its use in mild-to-moderate hypertension.

Authors:  M Asif A Siddiqui; Greg L Plosker
Journal:  Drugs       Date:  2004       Impact factor: 9.546

9.  Electronic pillboxes (MEMS) to assess the relationship between medication adherence and blood pressure control in primary care.

Authors:  Andreas Zeller; Knut Schroeder; Tim J Peters
Journal:  Scand J Prim Health Care       Date:  2007-12       Impact factor: 2.581

Review 10.  Safety and tolerability of eprosartan in combination with hydrochlorothiazide.

Authors:  Michael Böhm; Alisia Sachse
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

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