Literature DB >> 7561902

Spiganthine, the cardioactive principle of Spigelia anthelmia.

H Achenbach1, H Hübner, W Vierling, W Brandt, M Reiter.   

Abstract

Spiganthine [1] was isolated as the main cardioactive principle from medicinally used extracts of Spigelia anthelmia. Its structure was established by spectroscopic methods. The biological effect of spiganthine is characterized by a delay in contraction development of the heart muscle.

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Year:  1995        PMID： 7561902     DOI： 10.1021/np50121a019

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

1.  A 15-step synthesis of (+)-ryanodol.

Authors:  Kangway V Chuang; Chen Xu; Sarah E Reisman
Journal:  Science       Date:  2016-08-26       Impact factor: 47.728

2.  Synthesis of Complex Diterpenes: Strategies Guided by Oxidation Pattern Analysis.

Authors:  Sara E Dibrell; Yujia Tao; Sarah E Reisman
Journal:  Acc Chem Res       Date:  2021-02-23       Impact factor: 24.466

3.  Chemical Synthesis of (+)-Ryanodine and (+)-20-Deoxyspiganthine.

Authors:  Chen Xu; Arthur Han; Scott C Virgil; Sarah E Reisman
Journal:  ACS Cent Sci       Date:  2017-03-09       Impact factor: 14.553
  3 in total

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