AIMS: To examine the possibility that monocyte esterase deficiency (MED) could be caused by exposure to organophosphates. METHODS: Pseudocholinesterase, paraoxonase and arylesterase activities were measured in the serum and acetylcholinesterase activity was measured in the red cells of a group of monocyte esterase deficient subjects and compared with the enzyme activities of a control group of monocyte esterase positive subjects. RESULTS: No significant difference was found between the enzyme activities of the monocyte esterase deficient group and the control group for any of the esterases investigated. CONCLUSION: Current or recent exposure to organophosphorus is not the cause of MED.
AIMS: To examine the possibility that monocyte esterase deficiency (MED) could be caused by exposure to organophosphates. METHODS:Pseudocholinesterase, paraoxonase and arylesterase activities were measured in the serum and acetylcholinesterase activity was measured in the red cells of a group of monocyte esterase deficient subjects and compared with the enzyme activities of a control group of monocyte esterase positive subjects. RESULTS: No significant difference was found between the enzyme activities of the monocyte esterase deficient group and the control group for any of the esterases investigated. CONCLUSION: Current or recent exposure to organophosphorus is not the cause of MED.
Authors: C Mouchès; N Pasteur; J B Bergé; O Hyrien; M Raymond; B R de Saint Vincent; M de Silvestri; G P Georghiou Journal: Science Date: 1986-08-15 Impact factor: 47.728
Authors: E A Emmett; P G Lewis; F Tanaka; M Bleecker; R Fox; A C Darlington; D R Synkowski; A M Dannenberg; W J Taylor; M S Levine Journal: J Occup Med Date: 1985-12