Literature DB >> 7560180

Nuclear pseudoinclusions in melanocytic naevi and melanomas.

D S Rose1.   

Abstract

Melanocytes in melanocytic naevi and melanomas can display great variation. The presence of nuclear pseudoinclusions (NPI) is said to be useful in the histological and cytological differential diagnosis of malignant melanoma. The prevalence and characteristics of NPI in a series of 493 naevi and 50 melanomas are described. NPI were found in 31% of adult naevi, 30% of congenital naevi from children, 42% of Spitz naevi, 20% of dysplastic naevi, and 56% of melanomas. The presence of NPI is not a reliable criterion for differentiating melanoma from benign melanocytic lesions, although it is useful in distinguishing melanocytic from non-melanocytic tumours.

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Year:  1995        PMID: 7560180      PMCID: PMC502724          DOI: 10.1136/jcp.48.7.676

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  5 in total

1.  Spindle and epithelioid cell nevi in children and adults. A review of 211 cases of the Spitz nevus.

Authors:  D Weedon; J H Little
Journal:  Cancer       Date:  1977-07       Impact factor: 6.860

2.  Nonviral nuclear inclusions. I. Cytoplasmic invaginations.

Authors:  H J Sobel; R Schwarz; E Marquet
Journal:  Arch Pathol       Date:  1969-02

3.  Deep penetrating nevus.

Authors:  J A Seab; J H Graham; E B Helwig
Journal:  Am J Surg Pathol       Date:  1989-01       Impact factor: 6.394

4.  Nevus cell aggregates associated with lymph nodes: estimated frequency and clinical significance.

Authors:  R L Ridolfi; P P Rosen; H Thaler
Journal:  Cancer       Date:  1977-01       Impact factor: 6.860

5.  Fine needle aspirate smear morphology in metastatic melanoma.

Authors:  L J Layfield; N Ostrzega
Journal:  Acta Cytol       Date:  1989 Sep-Oct       Impact factor: 2.319

  5 in total
  3 in total

1.  Ubiquitin Immunostaining in Thyroid Neoplasms Marks True Intranuclear Cytoplasmic Pseudoinclusions and May Help Differentiate Papillary Carcinoma from NIFTP.

Authors:  Vincent Cracolici; Thomas Krausz; Nicole A Cipriani
Journal:  Head Neck Pathol       Date:  2018-03-06

Review 2.  Mucosal melanomas: a case-based review of the literature.

Authors:  Nagashree Seetharamu; Patrick A Ott; Anna C Pavlick
Journal:  Oncologist       Date:  2010-06-22

3.  A population-based analysis of germline BAP1 mutations in melanoma.

Authors:  Sally J O'Shea; Carla Daniela Robles-Espinoza; Lauren McLellan; Jeanine Harrigan; Xavier Jacq; James Hewinson; Vivek Iyer; Will Merchant; Faye Elliott; Mark Harland; D Timothy Bishop; Julia A Newton-Bishop; David J Adams
Journal:  Hum Mol Genet       Date:  2017-02-15       Impact factor: 6.150

  3 in total

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