Literature DB >> 7556597

The major acute phase serum protein in pigs is homologous to human plasma kallikrein sensitive PK-120.

N González-Ramón1, M A Alava, J A Sarsa, M Piñeiro, A Escartin, A Garcia-Gil, F Lampreave, A Piñeiro.   

Abstract

A major acute phase protein (pig-MAP) has been isolated from the sera of pigs after turpentine injection. The protein is the pig counterpart of a recently cloned human serum protein denominated PK-120, which is a putative substrate for kallikrein [Nishimura et al., 1995 FEBS Lett. 357, 207-211]. The protein exists in other mammalian species and it is also an acute phase protein, at least in the rat. Pig-MAP shows homology, as PK-120, with the heavy chain 2 (HC-2) of the inter-alpha-trypsin inhibitor superfamily but does not possess trypsin inhibitory activity.

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Year:  1995        PMID： 7556597     DOI： 10.1016/0014-5793(95)00882-a

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  11 in total

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