Literature DB >> 7552738

When one and one are not two.

R J Fletterick, J F Bazan.   

Abstract

Dimeric proteins can arise from monomers by the simple exchange of secondary structural elements or a wholesale swapping of domains. These results have implications for the construction of novel oligomeric molecules and illuminate how existing structures may have evolved.

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Year:  1995        PMID: 7552738     DOI: 10.1038/nsb0995-721

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN: 1072-8368


  2 in total

1.  The X-ray structure of a mutant eye lens beta B2-crystallin with truncated sequence extensions.

Authors:  B V Norledge; S Trinkl; R Jaenicke; C Slingsby
Journal:  Protein Sci       Date:  1997-08       Impact factor: 6.725

2.  A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission.

Authors:  Jonathan P B Lees; Cara Marie Manlandro; Lora K Picton; Alexandra Z Ebie Tan; Salvador Casares; John M Flanagan; Karen G Fleming; R Blake Hill
Journal:  J Mol Biol       Date:  2012-07-09       Impact factor: 5.469

  2 in total

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