Literature DB >> 7552159

Intracellular signalling. PI 3-kinase puts GTP on the Rac.

P J Parker1.   

Abstract

Phosphoinositide 3-kinase, an enzyme that is known to transduce signals received by a variety of receptor types, has been found to mediate agonist-dependent membrane ruffling via the small GTP-binding protein Rac.

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Year:  1995        PMID： 7552159     DOI： 10.1016/s0960-9822(95)00113-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  12 in total

1.  Acute morphogenic and chemotropic effects of neurotrophins on cultured embryonic Xenopus spinal neurons.

Authors:  G l Ming; A M Lohof; J Q Zheng
Journal:  J Neurosci       Date:  1997-10-15       Impact factor: 6.167

2.  Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly.

Authors:  S Potempa; A J Ridley
Journal:  Mol Biol Cell       Date:  1998-08       Impact factor: 4.138

3.  A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.

Authors:  J B Pracyk; K Tanaka; D D Hegland; K S Kim; R Sethi; I I Rovira; D R Blazina; L Lee; J T Bruder; I Kovesdi; P J Goldshmidt-Clermont; K Irani; T Finkel
Journal:  J Clin Invest       Date:  1998-09-01       Impact factor: 14.808

4.  Fast receptor-induced formation of glycerophosphoinositol-4-phosphate, a putative novel intracellular messenger in the Ras pathway.

Authors:  M Falasca; A Carvelli; C Iurisci; R G Qiu; M H Symons; D Corda
Journal:  Mol Biol Cell       Date:  1997-03       Impact factor: 4.138

Review 5.  The C2 domain calcium-binding motif: structural and functional diversity.

Authors:  E A Nalefski; J J Falke
Journal:  Protein Sci       Date:  1996-12       Impact factor: 6.725

Review 6.  CD28: a signalling perspective.

Authors:  S G Ward
Journal:  Biochem J       Date:  1996-09-01       Impact factor: 3.857

7.  Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression.

Authors:  G Fritz; B Kaina
Journal:  Mol Cell Biol       Date:  1999-03       Impact factor: 4.272

8.  Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

Authors:  S R James; C P Downes; R Gigg; S J Grove; A B Holmes; D R Alessi
Journal:  Biochem J       Date:  1996-05-01       Impact factor: 3.857

9.  Inositide signalling in Chlamydomonas: characterization of a phosphatidylinositol 3-kinase gene.

Authors:  A J Molendijk; R F Irvine
Journal:  Plant Mol Biol       Date:  1998-05       Impact factor: 4.076

10.  Activated R-ras, Rac1, PI 3-kinase and PKCepsilon can each restore cell spreading inhibited by isolated integrin beta1 cytoplasmic domains.

Authors:  A L Berrier; A M Mastrangelo; J Downward; M Ginsberg; S E LaFlamme
Journal:  J Cell Biol       Date:  2000-12-25       Impact factor: 10.539
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