Literature DB >> 7552048

Patient selection and remission rates with the current practice of electroconvulsive therapy in Germany.

J Kornhuber1, M Weller.   

Abstract

The current practice of German psychiatric hospitals restricts electroconvulsive therapy (ECT) to patients with profound disability and failure to respond to pharmacotherapy. We studied clinical features and seizure parameters in 63 patients who received ECT in a 3-year period at a German university hospital. Patients with unipolar and bipolar disorder (depressed) (n = 47) showed a complete or partial recovery as assessed 2 weeks after completion of the ECT course in 31.9 and 38.3%, respectively. Multiple linear regression analysis performed on several clinical and ECT seizure parameters failed to identify strong outcome predictors in our selected sample of patients. Most patients who eventually responded did so early in the course of ECT, while there was little improvement when > 10 ECT treatments were given. Our report highlights the efficacy of ECT in the management of severe psychiatric disorders even in a highly selected sample of patients previously found to be resistant to alternative modes of psychiatric treatment.

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Mesh:

Year:  1995        PMID: 7552048

Source DB:  PubMed          Journal:  Convuls Ther        ISSN: 0749-8055


  4 in total

1.  Treatment escalation in patients not responding to pharmacotherapy, psychotherapy, and electro-convulsive therapy: experiences from a novel regimen using intravenous S-ketamine as add-on therapy in treatment-resistant depression.

Authors:  Bernd Kallmünzer; Bastian Volbers; Anne Karthaus; Ozan Yüksel Tektas; Johannes Kornhuber; Helge H Müller
Journal:  J Neural Transm (Vienna)       Date:  2015-12-31       Impact factor: 3.575

2.  Contemporary use and practice of electroconvulsive therapy worldwide.

Authors:  Kari Ann Leiknes; Lindy Jarosh-von Schweder; Bjørg Høie
Journal:  Brain Behav       Date:  2012-05       Impact factor: 2.708

Review 3.  Therapeutic options for treatment-resistant depression.

Authors:  Richard C Shelton; Olawale Osuntokun; Alexandra N Heinloth; Sara A Corya
Journal:  CNS Drugs       Date:  2010-02       Impact factor: 5.749

4.  Intravenous theophylline is the most effective intervention to prolong EEG seizure duration in patients undergoing electroconvulsive therapy.

Authors:  Alexander Tzabazis; Michaela E Wiernik; Jan Wielopolski; Wolfgang Sperling; Harald Ihmsen; Hubert J Schmitt; Tino Münster
Journal:  BMC Anesthesiol       Date:  2017-08-29       Impact factor: 2.217

  4 in total

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