| Literature DB >> 7551221 |
G Ott1, G L Barchfeld, D Chernoff, R Radhakrishnan, P van Hoogevest, G Van Nest.
Abstract
MF59 is a safe, practical, and potent adjuvant for use with human vaccines. The formulation is easily manufactured, may be sterilized by filtration, and is both compatible and efficacious with all antigens tested to date. MF59 has been shown to be a potent stimulator of cellular and humoral responses to subunit antigens in both animal models and clinical studies. Toxicology studies in animal models and Phase I-III studies in humans have demonstrated the safety of MF59 with HSV, HIV, and influenza vaccines.Entities:
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Year: 1995 PMID： 7551221 DOI： 10.1007/978-1-4615-1823-5_10
Source DB: PubMed Journal: Pharm Biotechnol ISSN： 1078-0467