Literature DB >> 7549426

The molecular basis of fragile sites in human chromosomes.

G R Sutherland1, R I Richards.   

Abstract

Fragile sites on chromosomes have been classified into a number of groups according to their frequency and the conditions required to induce them. A number of the rare folate-sensitive fragile sites have been characterized and shown to be amplified methylated CCG trinucleotide repeats. One common fragile site has been partly characterized and appears to be a region of fragility, rather than a single site.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7549426     DOI： 10.1016/0959-437x(95)80046-8

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  30 in total

1.  Analysis of replication timing at the FRA10B and FRA16B fragile site loci.

Authors:  O Handt; E Baker; S Dayan; S M Gartler; E Woollatt; R I Richards; R S Hansen
Journal:  Chromosome Res       Date:  2000       Impact factor: 5.239

2.  Molecular basis for expression of common and rare fragile sites.

Authors:  Eitan Zlotorynski; Ayelet Rahat; Jennifer Skaug; Neta Ben-Porat; Efrat Ozeri; Ruth Hershberg; Ayala Levi; Stephen W Scherer; Hanah Margalit; Batsheva Kerem
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

3.  A fifth locus for Bardet-Biedl syndrome maps to chromosome 2q31.

Authors:  T L Young; L Penney; M O Woods; P S Parfrey; J S Green; D Hefferton; W S Davidson
Journal:  Am J Hum Genet       Date:  1999-03       Impact factor: 11.025

4.  Deletion at fragile sites is a common and early event in Barrett's esophagus.

Authors:  Lisa A Lai; Rumen Kostadinov; Michael T Barrett; Daniel A Peiffer; Dimitry Pokholok; Robert Odze; Carissa A Sanchez; Carlo C Maley; Brian J Reid; Kevin L Gunderson; Peter S Rabinovitch
Journal:  Mol Cancer Res       Date:  2010-07-20       Impact factor: 5.852

5.  A mechanism of palindromic gene amplification in Saccharomyces cerevisiae.

Authors:  Alison J Rattray; Brenda K Shafer; Beena Neelam; Jeffrey N Strathern
Journal:  Genes Dev       Date:  2005-06-01       Impact factor: 11.361

6.  The [(G/C)3NN]n motif: a common DNA repeat that excludes nucleosomes.

Authors:  Y H Wang; J D Griffith
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205

7.  Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

Authors:  D Mishmar; A Rahat; S W Scherer; G Nyakatura; B Hinzmann; Y Kohwi; Y Mandel-Gutfroind; J R Lee; B Drescher; D E Sas; H Margalit; M Platzer; A Weiss; L C Tsui; A Rosenthal; B Kerem
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205

8.  Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.

Authors:  Z Li; A Yu; A M Weiner
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

9.  Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.

Authors:  K A Smith; O B Chernova; R P Groves; M B Stark; J L Martínez; J N Davidson; J M Trent; T E Patterson; A Agarwal; P Duncan; M L Agarwal; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

10.  Autism Genetic Database (AGD): a comprehensive database including autism susceptibility gene-CNVs integrated with known noncoding RNAs and fragile sites.

Authors:  Gregory Matuszek; Zohreh Talebizadeh
Journal:  BMC Med Genet       Date:  2009-09-24       Impact factor: 2.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.