Literature DB >> 754819

A portable infusion pump, programmable with 16 rates.

J Bojsen, K Kølendorf, F Haslev, K Jørgensen.   

Abstract

An external, portable, programmable infusion pump has been developed for long-term therapeutic intravenous infusion of drugs. The impulse-controlled system consists of a 250 g CMOS-electronic unit, and an electromechanical infuser (250 g) containing a 10-ml disposable syringe. The infusion rate pattern is manually preprogrammed from 24 to 384 microliter/0.5 h. The coefficient of variation of the volume infused is less than 2% per. 0.5 h. The system has been tested by continuous administration of insulin in diabetics during 4 consecutive days, and can operate for 6-7 days with a 1 Ah, 5.4 V battery. The mean capillary blood glucose concentration could be maintained at levels close to normal (i.e. 7.0 mmol/1 +/- 2.3 (SD)) during the treatment period.

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Year:  1978        PMID: 754819

Source DB:  PubMed          Journal:  Biotelem Patient Monit        ISSN: 0378-309X


  5 in total

Review 1.  Optimisation of treatment by applying programmable rate-controlled drug delivery technology.

Authors:  Yie W Chien; Senshang Lin
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  Computed insulin profiles for normalization of glycemia in diabetic patients.

Authors:  J H Youn; H C Kim; H K Lee; B G Min
Journal:  Bull Math Biol       Date:  1983       Impact factor: 1.758

3.  The relationship between plasma concentration and plasma disappearance rate of immunoreactive insulin in normal subjects.

Authors:  S Fugleberg; K Kølendorf; B Thorsteinsson; H Bliddal; B Lund; F Bojsen
Journal:  Diabetologia       Date:  1982-06       Impact factor: 10.122

4.  Improvement of glucose homeostasis in insulin-dependent diabetics using a miniature insulin infusion pump with a fixed profile.

Authors:  K Køolendorf; J Bojsen; B Løorup
Journal:  Diabetologia       Date:  1980       Impact factor: 10.122

5.  A Survey of Insulin-Dependent Diabetes-Part II: Control Methods.

Authors:  Daisuke Takahashi; Yang Xiao; Fei Hu
Journal:  Int J Telemed Appl       Date:  2008
  5 in total

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