Literature DB >> 7548089

Interaction of brain spectrin (fodrin) with phospholipids.

W Diakowski1, A F Sikorski.   

Abstract

Binding of brain spectrin to frozen and thawed liposomes was studied, using a pelleting assay, as a function of lipid composition. Saturable binding was observed for all lipid mixtures that included aminophospholipids, as well as for the total lipid of synaptic plasma membranes. Binding was strong and saturable, with dissociation constants in the nanomolar range. There were two pH optima at ca. 6.0 and 7.5 and a sharp ionic strength optimum, corresponding to physiological solvent conditions. No competition could be detected with extraneous globular proteins, serum albumin, and hemoglobin. The results imply a strong, direct interaction between brain spectrin and the neuronal plasma membrane in the cell.

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Year:  1995        PMID： 7548089     DOI： 10.1021/bi00040a041

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  8 in total

1.  Organization and dynamics of tryptophan residues in brain spectrin: novel insight into conformational flexibility.

Authors:  Madhurima Mitra; Arunima Chaudhuri; Malay Patra; Chaitali Mukhopadhyay; Abhijit Chakrabarti; Amitabha Chattopadhyay
Journal:  J Fluoresc       Date:  2015-04-03       Impact factor: 2.217

2.  Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity.

Authors:  Michael J Volles; Peter T Lansbury
Journal:  J Mol Biol       Date:  2006-12-21       Impact factor: 5.469

3.  Brain spectrin (fodrin) interacts with phospholipids as revealed by intrinsic fluorescence quenching and monolayer experiments.

Authors:  W Diakowski; A Prychidny; M Swistak; M Nietubyć; K Białkowska; J Szopa; A F Sikorski
Journal:  Biochem J       Date:  1999-02-15       Impact factor: 3.857

4.  Interaction of dystrophin fragments with model membranes.

Authors:  C DeWolf; P McCauley; A F Sikorski; C P Winlove; A I Bailey; E Kahana; J C Pinder; W B Gratzer
Journal:  Biophys J       Date:  1997-06       Impact factor: 4.033

5.  Fluorescence study of the effect of cholesterol on spectrin-aminophospholipid interactions.

Authors:  Madhurima Mitra; Malay Patra; Abhijit Chakrabarti
Journal:  Eur Biophys J       Date:  2015-07-17       Impact factor: 1.733

6.  Superficial disposition of the N-terminal region of the surfactant protein SP-C and the absence of specific SP-B-SP-C interactions in phospholipid bilayers.

Authors:  I Plasencia; A Cruz; C Casals; J Pérez-Gil
Journal:  Biochem J       Date:  2001-11-01       Impact factor: 3.857

Review 7.  Spectrin and phospholipids - the current picture of their fascinating interplay.

Authors:  Dżamila M Bogusławska; Beata Machnicka; Anita Hryniewicz-Jankowska; Aleksander Czogalla
Journal:  Cell Mol Biol Lett       Date:  2014-02-25       Impact factor: 5.787

8.  Integrating Proteomes for Lung Tissues and Lavage Reveals Pathways That Link Responses in Allergen-Challenged Mice.

Authors:  Thomas H Mahood; Christopher D Pascoe; Tobias K Karakach; Aruni Jha; Sujata Basu; Peyman Ezzati; Victor Spicer; Neeloffer Mookherjee; Andrew J Halayko
Journal:  ACS Omega       Date:  2021-01-05
  8 in total

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