Literature DB >> 7548

Role of L-threonine dehydrogenase in the catabolism of threonine and synthesis of glycine by Escherichia coli.

E B Newman, V Kapoor, R Potter.   

Abstract

The enzyme L-threonine dehydrogenase was demonstrated in extracts of Escherichia coli K-12, and was shown to be the first enzyme of the pathway converting threonine to glycine. The enzyme was induced by L-leucine, but not by its substrate, L-threonine. The metabolic significance of leucine as a catabolic signal for amino acid degradation is considered.

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Year:  1976        PMID： 7548      PMCID： PMC233149          DOI： 10.1128/jb.126.3.1245-1249.1976

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  18 in total

1.  Regulation of proline catabolism by leucyl,phenylalanyl-tRNA-protein transferase.

Authors:  C E Deutch; R L Soffer
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

2.  DETERMINATION OF CARBONYL COMPOUNDS WITH N-METHYL BENZOTHIAZOLONE HYDRAZONE.

Authors:  M A PAZ; O O BLUMENFELD; M ROJKIND; E HENSON; C FURFINE; P M GALLOP
Journal:  Arch Biochem Biophys       Date:  1965-03       Impact factor: 4.013

3.  Biosynthesis of alpha-aminoketones and the metabolism of aminoacetone.

Authors:  G URATA; S GRANICK
Journal:  J Biol Chem       Date:  1963-02       Impact factor: 5.157

4.  Aspects of the metabolism of glycine and of porphyrins.

Authors:  A NEUBERGER
Journal:  Biochem J       Date:  1961-01       Impact factor: 3.857

5.  Aminoacetone formation by Staphylococcus aureus.

Authors:  W H ELLIOTT
Journal:  Biochem J       Date:  1960-03       Impact factor: 3.857

6.  Induced formation of serine and threonine deaminases by Escherichia coli.

Authors:  A B PARDEE; L S PRESTIDGE
Journal:  J Bacteriol       Date:  1955-12       Impact factor: 3.490

7.  Threonine deamination in Escherichia coli. II. Evidence for two L-threonine deaminases.

Authors:  H E UMBARGER; B BROWN
Journal:  J Bacteriol       Date:  1957-01       Impact factor: 3.490

8.  The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine.

Authors:  D MAUZERALL; S GRANICK
Journal:  J Biol Chem       Date:  1956-03       Impact factor: 5.157

9.  The enzymic formation of aminoacetone from threonine and its further metabolism.

Authors:  M L Green; W H Elliott
Journal:  Biochem J       Date:  1964-09       Impact factor: 3.857

10.  Derivation of glycine from threonine in Escherichia coli K-12 mutants.

Authors:  J Fraser; E B Newman
Journal:  J Bacteriol       Date:  1975-06       Impact factor: 3.490
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  23 in total

1.  The lrp gene product regulates expression of lysU in Escherichia coli K-12.

Authors:  R Lin; B Ernsting; I N Hirshfield; R G Matthews; F C Neidhardt; R L Clark; E B Newman
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

2.  The tdh and serA operons of Escherichia coli: mutational analysis of the regulatory elements of leucine-responsive genes.

Authors:  J H Rex; B D Aronson; R L Somerville
Journal:  J Bacteriol       Date:  1991-10       Impact factor: 3.490

3.  Structural and functional analysis of a cloned segment of Escherichia coli DNA that specifies proteins of a C4 pathway of serine biosynthesis.

Authors:  P D Ravnikar; R L Somerville
Journal:  J Bacteriol       Date:  1987-10       Impact factor: 3.490

4.  Activation of a cryptic pathway for threonine metabolism via specific IS3-mediated alteration of promoter structure in Escherichia coli.

Authors:  B D Aronson; M Levinthal; R L Somerville
Journal:  J Bacteriol       Date:  1989-10       Impact factor: 3.490

Review 5.  The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli.

Authors:  J M Calvo; R G Matthews
Journal:  Microbiol Rev       Date:  1994-09

6.  Localization of the structural gene for threonine dehydrogenase in Escherichia coli.

Authors:  P D Ravnikar; R L Somerville
Journal:  J Bacteriol       Date:  1986-10       Impact factor: 3.490

7.  2-Aminoacrylate Stress Induces a Context-Dependent Glycine Requirement in ridA Strains of Salmonella enterica.

Authors:  Dustin C Ernst; Diana M Downs
Journal:  J Bacteriol       Date:  2015-11-16       Impact factor: 3.490

8.  Threonine formation via the coupled activity of 2-amino-3-ketobutyrate coenzyme A lyase and threonine dehydrogenase.

Authors:  J P Marcus; E E Dekker
Journal:  J Bacteriol       Date:  1993-10       Impact factor: 3.490

9.  Threonine degradation by Serratia marcescens.

Authors:  S Komatsubara; K Murata; M Kisumi; I Chibata
Journal:  J Bacteriol       Date:  1978-08       Impact factor: 3.490

10.  purU, a source of formate for purT-dependent phosphoribosyl-N-formylglycinamide synthesis.

Authors:  P L Nagy; G M McCorkle; H Zalkin
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490
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