Literature DB >> 7546390

Analysis of immunoglobulin gene rearrangements in single B cells.

A Ehlich1, R Küppers.   

Abstract

The polymerase chain reaction allows the characterization of RNA and DNA sequences in samples as small as a single cell. The recent development of amplification systems designed to isolate rearranged immunoglobulin genes from single B lineage cells has provided a powerful tool to investigate various aspects of B-cell development.

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Year:  1995        PMID： 7546390     DOI： 10.1016/0952-7915(95)80016-6

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  5 in total

1.  Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease.

Authors:  T Goossens; U Klein; R Küppers
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

2.  Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing.

Authors:  Li Bai; Yuhong Chen; Yinghong He; Xuezhi Dai; Xueyan Lin; Renren Wen; Demin Wang
Journal:  Mol Cell Biol       Date:  2007-06-25       Impact factor: 4.272

Review 3.  Immunomodulation by lead.

Authors:  Vijay K Singh; Kamla P Mishra; Reena Rani; Virendra S Yadav; Sudhir K Awasthi; Satyendra K Garg
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

4.  Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition.

Authors:  F Papavasiliou; M Jankovic; M C Nussenzweig
Journal:  J Exp Med       Date:  1996-11-01       Impact factor: 14.307

Review 5.  Single B cell antibody technologies.

Authors:  Thomas Tiller
Journal:  N Biotechnol       Date:  2011-04-05       Impact factor: 5.079
  5 in total

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