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Literature DB >> 7546382

Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms.

Abstract

During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.

Entities: Disease Gene

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Year: 1995 PMID： 7546382 DOI： 10.1016/0952-7915(95)80007-7

Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486

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Cited

20 in total

Review 1. The concept of space and competition in immune regulation.

Authors: Brigitta Stockinger; Thomas Barthlott; George Kassiotis
Journal: Immunology Date: 2004-03 Impact factor: 7.397

2. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis.

Authors: R J Grumont; I J Rourke; S Gerondakis
Journal: Genes Dev Date: 1999-02-15 Impact factor: 11.361

Review 3. Apoptosis in B-chronic lymphocytic leukaemia.

Authors: L M Osorio; M Aguilar-Santelises
Journal: Med Oncol Date: 1998-12 Impact factor: 3.064

4. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes.

Authors: K Newton; A W Harris; M L Bath; K G Smith; A Strasser
Journal: EMBO J Date: 1998-02-02 Impact factor: 11.598

5. The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.

Authors: M Grossmann; L A O'Reilly; R Gugasyan; A Strasser; J M Adams; S Gerondakis
Journal: EMBO J Date: 2000-12-01 Impact factor: 11.598

6. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

Authors: M Grell; G Zimmermann; E Gottfried; C M Chen; U Grünwald; D C Huang; Y H Wu Lee; H Dürkop; H Engelmann; P Scheurich; H Wajant; A Strasser
Journal: EMBO J Date: 1999-06-01 Impact factor: 11.598

Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms.

Review 1. The concept of space and competition in immune regulation.

2. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis.

Review 3. Apoptosis in B-chronic lymphocytic leukaemia.

4. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes.

5. The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.

6. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

7. FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen.

8. Transforming growth factor-beta promotes 'death by neglect' in post-activated human T cells.

9. DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis.

10. In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1.