| Literature DB >> 7546379 |
Abstract
Clonal elimination accounts for self-tolerance induction in the thymus and also affects mature T cells responding to exogenous antigens in the periphery. Recent evidence on the microenvironments, cell-cell interactions and signalling requirements for clonal deletion of immature and mature T cells is discussed.Mesh:
Year: 1995 PMID: 7546379 DOI: 10.1016/0952-7915(95)80004-2
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486