Literature DB >> 7546330

Effects of aminotriazole on ethanol, water, and food intake and on brain catalase in UChA and UChB rats.

L Tampier1, M E Quintanilla, J Mardones.   

Abstract

Aminotriazole (AT), a catalase inhibitor, was administered to UChA (low ethanol consumer) and UChB (high ethanol consumer) rats. Ethanol, water, and solid food intake were measured during basic, treatment, and posttreatment periods. The effects of AT on brain catalase activity and acetaldehyde recovered during incubation of brain homogenates with ethanol were also studied in rats of both strains. Results showed that AT decreased voluntary ethanol intake in UChB rats, and also diminished the consumption of food by rats of both strains. No strain difference in brain catalase activity and acetaldehyde recovered during ethanol incubation was observed. The results suggest that AT effect on ethanol consumption is secondary to a reduction in the appetite for calories and not related to its catalase blocking effect.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7546330     DOI： 10.1016/0741-8329(95)00014-i

Source DB:  PubMed          Journal:  Alcohol        ISSN： 0741-8329            Impact factor:   2.405


  11 in total

Review 1.  Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options.

Authors:  María Elena Quintanilla; Fernando Ezquer; Paola Morales; Mario Rivera-Meza; Eduardo Karahanian; Marcelo Ezquer; Mario Herrera-Marschitz
Journal:  Gene Ther       Date:  2019-02-28       Impact factor: 5.250

2.  Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects.

Authors:  Eduardo Karahanian; María Elena Quintanilla; Lutske Tampier; Mario Rivera-Meza; Diego Bustamante; Víctor Gonzalez-Lira; Paola Morales; Mario Herrera-Marschitz; Yedy Israel
Journal:  Alcohol Clin Exp Res       Date:  2011-02-17       Impact factor: 3.455

Review 3.  What is in that drink: the biological actions of ethanol, acetaldehyde, and salsolinol.

Authors:  Gerald A Deehan; Mark S Brodie; Zachary A Rodd
Journal:  Curr Top Behav Neurosci       Date:  2013

4.  Central reinforcing effects of ethanol are blocked by catalase inhibition.

Authors:  Michael E Nizhnikov; Juan C Molina; Norman E Spear
Journal:  Alcohol       Date:  2007-11       Impact factor: 2.405

5.  Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the H₂O₂ scavenger alpha lipoic acid.

Authors:  Juan Carlos Ledesma; Carlos M G Aragon
Journal:  Psychopharmacology (Berl)       Date:  2012-08-11       Impact factor: 4.530

6.  Ethanol-derived acetaldehyde: pleasure and pain of alcohol mechanism of action.

Authors:  Giulia Muggironi; Giulia R Fois; Marco Diana
Journal:  Front Behav Neurosci       Date:  2013-07-17       Impact factor: 3.558

Review 7.  From Ethanol to Salsolinol: Role of Ethanol Metabolites in the Effects of Ethanol.

Authors:  Alessandra T Peana; Michela Rosas; Simona Porru; Elio Acquas
Journal:  J Exp Neurosci       Date:  2016-11-20

Review 8.  Acetaldehyde, Motivation and Stress: Behavioral Evidence of an Addictive ménage à trois.

Authors:  Anna Brancato; Gianluca Lavanco; Angela Cavallaro; Fulvio Plescia; Carla Cannizzaro
Journal:  Front Behav Neurosci       Date:  2017-02-09       Impact factor: 3.558

9.  Gene specific modifications unravel ethanol and acetaldehyde actions.

Authors:  Yedy Israel; Mario Rivera-Meza; Eduardo Karahanian; María E Quintanilla; Lutske Tampier; Paola Morales; Mario Herrera-Marschitz
Journal:  Front Behav Neurosci       Date:  2013-07-08       Impact factor: 3.558

10.  Elucidating the biological basis for the reinforcing actions of alcohol in the mesolimbic dopamine system: the role of active metabolites of alcohol.

Authors:  Gerald A Deehan; Sheketha R Hauser; Jessica A Wilden; William A Truitt; Zachary A Rodd
Journal:  Front Behav Neurosci       Date:  2013-08-23       Impact factor: 3.558
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.