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Literature DB >> 7546210

High endothelial venules (HEVs): specialized endothelium for lymphocyte migration.

Abstract

High endothelial venules (HEVs) are specialized postcapillary venules found in lymphoid tissues that support high levels of lymphocyte extravasation from the blood. Here, Jean-Philippe Girard and Timothy Springer highlight the unique properties of HEV endothelium, discuss the molecular mechanisms controlling HEV specialization and review evidence suggesting that HEVs could play an important role in the pathogenesis of chronic inflammatory diseases.

Entities: Disease Species

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Year: 1995 PMID： 7546210 DOI： 10.1016/0167-5699(95)80023-9

Source DB: PubMed Journal: Immunol Today ISSN： 0167-5699

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Cited

133 in total

Review 1. Molecules controlling lymphocyte migration to the gut.

Authors: M Salmi; S Jalkanen
Journal: Gut Date: 1999-07 Impact factor: 23.059

2. Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection.

Authors: S D Rosen
Journal: Am J Pathol Date: 1999-10 Impact factor: 4.307

Review 3. Adhesion of lymphocytes to hepatic endothelium.

Authors: P F Lalor; D H Adams
Journal: Mol Pathol Date: 1999-08

4. The monocyte chemotactic protein a (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours.

Authors: M G Luciani; A Stoppacciaro; G Peri; A Mantovani; L P Ruco
Journal: Mol Pathol Date: 1998-10

Review 5. T lymphocyte and fibroblast interactions: the case of skin involvement in systemic sclerosis and other examples.

Authors: C Chizzolini
Journal: Springer Semin Immunopathol Date: 1999

10. Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma.

Authors: Anna M Wirsing; Oddveig G Rikardsen; Sonja E Steigen; Lars Uhlin-Hansen; Elin Hadler-Olsen
Journal: Tumour Biol Date: 2015-09-17

High endothelial venules (HEVs): specialized endothelium for lymphocyte migration.

Review 1. Molecules controlling lymphocyte migration to the gut.

2. Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection.

Review 3. Adhesion of lymphocytes to hepatic endothelium.

4. The monocyte chemotactic protein a (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours.

Review 5. T lymphocyte and fibroblast interactions: the case of skin involvement in systemic sclerosis and other examples.

6. L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis.

7. Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules.

Review 8. Role of cell adhesion molecules in leukocyte recruitment in the liver and gut.

9. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules.

10. Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma.