Literature DB >> 7545808

Epitopes in the 19kDa fragment of the Plasmodium falciparum major merozoite surface protein-1 (PfMSP-1(19)) recognized by human antibodies.

S Shai1, M J Blackman, A A Holder.   

Abstract

The antibody response to two different epitopes located in the C-terminal 19kDa fragment of the Plasmodium falciparum merozoite surface protein-1 (MSP-1(19)) has been studied using a competitive ELISA based on the inhibition of monoclonal antibody (MoAb) binding by serum samples. Sera from children aged three to eight years who suffered clinical symptoms of malaria, or were partially immune with an asymptomatic infection, and from adults all living in The Gambia, West Africa were tested. The results suggest that the antibody response to MSP-1(19) has a role in naturally-acquired immunity in Gambian individuals.

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Year:  1995        PMID： 7545808     DOI： 10.1111/j.1365-3024.1995.tb01025.x

Source DB:  PubMed          Journal:  Parasite Immunol        ISSN： 0141-9838            Impact factor:   2.280


  9 in total

1.  Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria.

Authors:  D Dodoo; T G Theander; J A Kurtzhals; K Koram; E Riley; B D Akanmori; F K Nkrumah; L Hviid
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

2.  A reduced risk of infection with Plasmodium vivax and clinical protection against malaria are associated with antibodies against the N terminus but not the C terminus of merozoite surface protein 1.

Authors:  Paulo Afonso Nogueira; Fabiana Piovesan Alves; Carmen Fernandez-Becerra; Oliver Pein; Neida Rodrigues Santos; Luiz Hildebrando Pereira da Silva; Erney Plessman Camargo; Hernando A del Portillo
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

3.  Inhibitory antibodies specific for the 19-kilodalton fragment of merozoite surface protein 1 do not correlate with delayed appearance of infection with Plasmodium falciparum in semi-immune individuals in Vietnam.

Authors:  E Elsa Herdiana Murhandarwati; Lina Wang; Casilda G Black; Doan Hanh Nhan; Thomas L Richie; Ross L Coppel
Journal:  Infect Immun       Date:  2009-07-20       Impact factor: 3.441

4.  Partial protection against Plasmodium vivax blood-stage infection in Saimiri monkeys by immunization with a recombinant C-terminal fragment of merozoite surface protein 1 in block copolymer adjuvant.

Authors:  C Yang; W E Collins; J S Sullivan; D C Kaslow; L Xiao; A A Lal
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

5.  Natural immune response to the C-terminal 19-kilodalton domain of Plasmodium falciparum merozoite surface protein 1.

Authors:  Y P Shi; U Sayed; S H Qari; J M Roberts; V Udhayakumar; A J Oloo; W A Hawley; D C Kaslow; B L Nahlen; A A Lal
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

6.  Naturally acquired antibody responses to Plasmodium falciparum merozoite surface protein 4 in a population living in an area of endemicity in Vietnam.

Authors:  L Wang; T L Richie; A Stowers; D H Nhan; R L Coppel
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

7.  Non-variant specific antibody responses to the C-terminal region of merozoite surface protein-1 of Plasmodium falciparum (PfMSP-1(19)) in Iranians exposed to unstable malaria transmission.

Authors:  Sedigheh Zakeri; Akram A Mehrizi; Samaneh Zoghi; Navid D Djadid
Journal:  Malar J       Date:  2010-09-16       Impact factor: 2.979

8.  Linkage of exogenous T-cell epitopes to the 19-kilodalton region of Plasmodium yoelii merozoite surface protein 1 (MSP1(19)) can enhance protective immunity against malaria and modulate the immunoglobulin subclass response to MSP1(19).

Authors:  N Ahlborg; I T Ling; A A Holder; E M Riley
Journal:  Infect Immun       Date:  2000-04       Impact factor: 3.441

9.  Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans.

Authors:  Danny W Wilson; Freya J I Fowkes; Paul R Gilson; Salenna R Elliott; Livingstone Tavul; Pascal Michon; Elija Dabod; Peter M Siba; Ivo Mueller; Brendan S Crabb; James G Beeson
Journal:  PLoS One       Date:  2011-11-15       Impact factor: 3.240
  9 in total

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