Literature DB >> 7543152

Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections.

E De Clercq1.   

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Year:  1995        PMID: 7543152     DOI: 10.1021/jm00014a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  41 in total

1.  Inactivation of cysteine proteases by peptidyl epoxides: characterization of the alkylation sites on the enzyme and the inactivator.

Authors:  A Albeck; S Kliper
Journal:  Biochem J       Date:  2000-02-15       Impact factor: 3.857

2.  3D-QSAR and molecular modeling of HIV-1 integrase inhibitors.

Authors:  Mahindra T Makhija; Vithal M Kulkarni
Journal:  J Comput Aided Mol Des       Date:  2002-03       Impact factor: 3.686

3.  Hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi as a target for structure-based inhibitor design: crystallization and inhibition studies with purine analogs.

Authors:  A E Eakin; A Guerra; P J Focia; J Torres-Martinez; S P Craig
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

4.  Investigation of formation, recognition, stabilization, and conversion of dimeric G-quadruplexes of HIV-1 integrase inhibitors by electrospray ionization mass spectrometry.

Authors:  Huihui Li; Gu Yuan; Daming Du
Journal:  J Am Soc Mass Spectrom       Date:  2008-02-05       Impact factor: 3.109

5.  Stability of UC-781, in intestinal mucosal homogenates of the rat, rabbit, and pig.

Authors:  G Van den Mooter; G Stas; F Damian; L Naesens; J Balzarini; R Kinget; P Augustijns
Journal:  Pharm Res       Date:  1998-11       Impact factor: 4.200

6.  PAPQMD parametrization of molecular systems with cyclopropyl rings: conformational study of homopeptides constituted by 1-aminocyclopropane-1-carboxylic acid.

Authors:  C Alemán; J Casanovas; S E Galembeck
Journal:  J Comput Aided Mol Des       Date:  1998-05       Impact factor: 3.686

7.  Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.

Authors:  Horrick Sharma; Shivaputra Patil; Tino W Sanchez; Nouri Neamati; Raymond F Schinazi; John K Buolamwini
Journal:  Bioorg Med Chem       Date:  2011-03-01       Impact factor: 3.641

8.  Structure-activity correlation study of HIV-1 inhibitors: electronic and molecular parameters.

Authors:  S Hannongbua; L Lawtrakul; J Limtrakul
Journal:  J Comput Aided Mol Des       Date:  1996-04       Impact factor: 3.686

9.  Mechanism of polyoxometalate-mediated inactivation of DNA polymerases: an analysis with HIV-1 reverse transcriptase indicates specificity for the DNA-binding cleft.

Authors:  S G Sarafianos; U Kortz; M T Pope; M J Modak
Journal:  Biochem J       Date:  1996-10-15       Impact factor: 3.857

10.  Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.

Authors:  Valery Fikkert; Bénédicte Van Maele; Jo Vercammen; Anke Hantson; Barbara Van Remoortel; Martine Michiels; Cristina Gurnari; Christophe Pannecouque; Marc De Maeyer; Yves Engelborghs; Erik De Clercq; Zeger Debyser; Myriam Witvrouw
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103

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