Literature DB >> 7540348

The effect of colchicine and vinblastine on bleomycin-induced lung fibrosis in rats.

A Ledwozyw1.   

Abstract

The effect of colchicine and vinblastine on collagenase, lysyl oxidase and prolyl hydroxylase activities as well as on collagen cross-linking and types of this protein in bleomycin induced lung fibrosis in rats was investigated. Both colchicine and vinblastine diminish bleomycin-induced changes in the above-mentioned enzyme activities as well as collagen cross-linking and normalize type I/type III collagen ratio.

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Year:  1994        PMID: 7540348

Source DB:  PubMed          Journal:  Acta Physiol Hung        ISSN: 0231-424X


  2 in total

1.  Inhibition of respiratory syncytial virus replication and suppression of RSV-induced airway inflammation in neonatal rats by colchicine.

Authors:  Nihong Lu; Yongrui Yang; Honglu Liu; Xiangli Ding; Yangbing Ou; Jiawei Xia; Yingrong Du
Journal:  3 Biotech       Date:  2019-10-10       Impact factor: 2.406

Review 2.  The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

Authors:  Antje Moeller; Kjetil Ask; David Warburton; Jack Gauldie; Martin Kolb
Journal:  Int J Biochem Cell Biol       Date:  2007-08-30       Impact factor: 5.085

  2 in total

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