Literature DB >> 7540121

The nephrotoxicity of immunosuppressive drugs.

W M Bennett1.   

Abstract

Nephrotoxicity from immunosuppressive drugs can complicate otherwise successful therapy. This paper reviews the clinical and pathophysiologic aspects of nephrotoxicity. The chronic progressive nephropathy is emphasized based on a recently developed animal model. Experimental and clinical data regarding FK506, new cyclosporine analogs, and Rapamycin are also discussed.

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Year:  1995        PMID: 7540121

Source DB:  PubMed          Journal:  Clin Nephrol        ISSN: 0301-0430            Impact factor:   0.975


  4 in total

Review 1.  Isolated glomeruli and cultured mesangial cells as in vitro models to study immunosuppressive agents.

Authors:  M Potier; B L'Azou; J Cambar
Journal:  Cell Biol Toxicol       Date:  1996-12       Impact factor: 6.691

2.  Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.

Authors:  Craig Slattery; Eric Campbell; Tara McMorrow; Michael P Ryan
Journal:  Am J Pathol       Date:  2005-08       Impact factor: 4.307

3.  Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A.

Authors:  Akira Ikari; Chiaki Okude; Hayato Sawada; Tadanobu Takahashi; Junko Sugatani; Masao Miwa
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2007-11-17       Impact factor: 3.000

4.  The use of everolimus in renal-transplant patients.

Authors:  Julio Pascual
Journal:  Int J Nephrol Renovasc Dis       Date:  2009-06-02
  4 in total

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