| Literature DB >> 7539627 |
N J Bishop1, D M Williams, J C Compston, D M Stirling, A Prentice.
Abstract
Recombinant human granulocyte colony-stimulating factor (G-CSF) has substantially improved life expectancy for children with severe congenital neutropenia (SCN). Severe osteoporosis, reported in this population, may relate to the disease process, or be a therapeutic side-effect. This report details bone loss, quantitated absorptiometrically and histomorphometrically, in a child with SCN and vertebral collapse, and the positive response to anabolic steroid and bisphosphonate therapy.Entities:
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Year: 1995 PMID： 7539627 DOI： 10.1111/j.1365-2141.1995.tb08441.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998