Literature DB >> 7538722

Recurrent anaplastic ependymoma with an abnormal karyotype and c-myc proto-oncogene overexpression.

M Debiec-Rychter1, J Lasota, J Alwasiak, P P Liberski.   

Abstract

Cytogenetic analysis on a supratentorial, recurrent, anaplastic ependymoma from a 29-year-old female disclosed the presence of an abnormal clone with the karyotype 46,XX,der(8)t(8;11)(q24;p11),-11,add(?)t(?;11)(?;q13). By the Northern hybridization assay and immunohistochemical staining, tumor cells revealed overexpression of c-myc proto-oncogene, although no evidence of amplification or structural rearrangement of this gene was found.

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Year:  1995        PMID: 7538722     DOI: 10.1007/bf00309343

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN: 0001-6322            Impact factor:   17.088


  22 in total

1.  Chromosome abnormalities in low-grade central nervous system tumors.

Authors:  C A Griffin; P P Long; B S Carson; H Brem
Journal:  Cancer Genet Cytogenet       Date:  1992-05

2.  Elevated c-myc expression in childhood medulloblastomas.

Authors:  D N MacGregor; E B Ziff
Journal:  Pediatr Res       Date:  1990-07       Impact factor: 3.756

3.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

4.  Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.

Authors:  P A Hieter; E E Max; J G Seidman; J V Maizel; P Leder
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

5.  The structure and nucleotide sequence of the 5' end of the human c-myc oncogene.

Authors:  R Watt; K Nishikura; J Sorrentino; A ar-Rushdi; C M Croce; G Rovera
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

6.  Application of long-term collagenase disaggregation for the cytogenetic analysis of human solid tumors.

Authors:  J Limon; P Dal Cin; A A Sandberg
Journal:  Cancer Genet Cytogenet       Date:  1986-12

Review 7.  The new WHO classification of brain tumours.

Authors:  P Kleihues; P C Burger; B W Scheithauer
Journal:  Brain Pathol       Date:  1993-07       Impact factor: 6.508

8.  Cytogenetic analysis of 109 pediatric central nervous system tumors.

Authors:  E Neumann; D K Kalousek; M G Norman; P Steinbok; D D Cochrane; K Goddard
Journal:  Cancer Genet Cytogenet       Date:  1993-11

9.  Analysis of the 3' flanking region of the human c-myc gene in lymphomas with the t(8;22) and t(2;8) chromosomal translocations.

Authors:  L K Sun; L C Showe; C M Croce
Journal:  Nucleic Acids Res       Date:  1986-05-27       Impact factor: 16.971

10.  Cytogenetic abnormalities in human ependymomas.

Authors:  M R Stratton; J Darling; P L Lantos; C S Cooper; B R Reeves
Journal:  Int J Cancer       Date:  1989-10-15       Impact factor: 7.396

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  1 in total

1.  Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas.

Authors:  Margaret Shatara; Kathleen M Schieffer; Darren Klawinski; Diana L Thomas; Christopher R Pierson; Eric A Sribnick; Jeremy Jones; Diana P Rodriguez; Carol Deeg; Elizabeth Hamelberg; Stephanie LaHaye; Katherine E Miller; James Fitch; Benjamin Kelly; Kristen Leraas; Ruthann Pfau; Peter White; Vincent Magrini; Richard K Wilson; Elaine R Mardis; Mohamed S Abdelbaki; Jonathan L Finlay; Daniel R Boué; Catherine E Cottrell; David R Ghasemi; Kristian W Pajtler; Diana S Osorio
Journal:  Acta Neuropathol Commun       Date:  2021-12-11       Impact factor: 7.801

  1 in total

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