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Literature DB >> 7538506

CM101, a polysaccharide antitumor agent, does not inhibit wound healing in murine models.

T E Quinn¹, G B Thurman, A K Sundell, M Zhang, C G Hellerqvist.

Abstract

CM101 (previously called GBS toxin), a new anticancer polysaccharide that induces inflammatory reactions in neovasculature of tumors, does not cause similar reactions in neovasculature of healing wounds. It appears that treatment with CM101 will not interfere with normal wound healing in cancer patients.

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Year: 1995 PMID： 7538506 DOI： 10.1007/bf01366971

Source DB: PubMed Journal: J Cancer Res Clin Oncol ISSN： 0171-5216 Impact factor: 4.553

16 in total

1. Stimulation of fibroplasia in rats by bovine cartilage powder.

Authors: S C Woodward; J B Herrmann
Journal: Arch Surg Date: 1968-02

2. Studies on group B beta-hemolytic Streptococcus. I. Isolation and partial characterization of an extracellular toxin.

Authors: C G Hellerqvist; J Rojas; R S Green; S Sell; H Sundell; M T Stahlman
Journal: Pediatr Res Date: 1981-06 Impact factor: 3.756

3. Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid.

Authors: S Hase; S Nakazawa; Y Tsukamoto; K Segawa
Journal: Digestion Date: 1989 Impact factor: 3.216

4. Mechanism of action of angiostatic steroids: suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis.

Authors: F Blei; E L Wilson; P Mignatti; D B Rifkin
Journal: J Cell Physiol Date: 1993-06 Impact factor: 6.384

5. Effects of group B Streptococcus toxin on long-term survival of mice bearing transplanted Madison lung tumors.

Authors: G B Thurman; B A Russel; G E York; Y F Wang; D L Page; H W Sundell; C G Hellerqvist
Journal: J Cancer Res Clin Oncol Date: 1994 Impact factor: 4.553

6. Antitumor effects of GBS toxin: a polysaccharide exotoxin from group B beta-hemolytic streptococcus.

Authors: C G Hellerqvist; G B Thurman; D L Page; Y F Wang; B A Russell; C A Montgomery; H W Sundell
Journal: J Cancer Res Clin Oncol Date: 1993 Impact factor: 4.553

7. Pulmonary hemodynamic and ultrastructural changes associated with Group B streptococcal toxemia in adult sheep and newborn lambs.

Authors: J Rojas; L E Larsson; C G Hellerqvist; K L Brigham; M E Gray; M T Stahlman
Journal: Pediatr Res Date: 1983-12 Impact factor: 3.756

CM101, a polysaccharide antitumor agent, does not inhibit wound healing in murine models.

1. Stimulation of fibroplasia in rats by bovine cartilage powder.

2. Studies on group B beta-hemolytic Streptococcus. I. Isolation and partial characterization of an extracellular toxin.

3. Effects of prednisolone and human epidermal growth factor on angiogenesis in granulation tissue of gastric ulcer induced by acetic acid.

4. Mechanism of action of angiostatic steroids: suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis.

5. Effects of group B Streptococcus toxin on long-term survival of mice bearing transplanted Madison lung tumors.

6. Antitumor effects of GBS toxin: a polysaccharide exotoxin from group B beta-hemolytic streptococcus.

7. Pulmonary hemodynamic and ultrastructural changes associated with Group B streptococcal toxemia in adult sheep and newborn lambs.

8. Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer.

9. Epidermal growth factor increases granulation tissue formation dose dependently.

10. Acidic fibroblast growth factor accelerates the healing of acetic-acid-induced gastric ulcers in rats.

1. Acute inflammatory changes in subcutaneous microtumors in the ears of mice induced by intravenous CM101 (GBS toxin).