Literature DB >> 7537179

Novel fluoroprostacyclin analogs with modified cycloalkylenyl chains. Highly potent and orally active anti-anginal agents.

Y Matsumura1, T Asai, T Shimada, T Nakayama, M Urushihara, Y Morizawa, A Yasuda, T Yamamoto, B Fujitani, K Hosoki.   

Abstract

Novel fluoroprostacyclin analogs (1a-f) have been synthesized and pharmacologically evaluated. Compounds 1a-c given intravenously or orally showed potent and long-lasting anti-anginal activities in an animal model.

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Year:  1995        PMID: 7537179     DOI: 10.1248/cpb.43.353

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Synthesis and conformational behavior of the difluoromethylene linked C-glycoside analog of beta-galactopyranosyl-(1<-->1)-alpha-mannopyranoside.

Authors:  Richard W Denton; Kurissery A Tony; José Juan Hernández-Gay; F Javier Cañada; Jesús Jiménez-Barbero; David R Mootoo
Journal:  Carbohydr Res       Date:  2007-06-13       Impact factor: 2.104

  1 in total

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