PURPOSE: To determine if neuroimaging findings in infants who undergo extracorporeal membrane oxygenation (ECMO) are predictive of developmental outcome. MATERIALS AND METHODS: At 1-2 years of age, 183 ECMO survivors (69 female, 114 male) underwent developmental examination. Neuroimaging studies obtained at time of ECMO were assigned a neuroimaging score. Neuroimaging findings were correlated with developmental outcome. RESULTS: Eighty-five infants had neuroimaging abnormalities. Development was normal in 105 infants, suspect in 37, and delayed in 41. Mean neuroimaging scores were significantly worse in survivors with delayed development (P < or = .0001). The sensitivity and specificity of normal neuroimaging findings in prediction of normal outcome were 65% and 63%, respectively. Survivors with nonhemorrhagic abnormalities had a higher risk of delayed development than did those with isolated hemorrhagic abnormalities (39% vs 21%). CONCLUSION: Although they cannot be used alone to predict outcome, early neuroimaging scores can be used to assign risk categories for developmental outcome.
PURPOSE: To determine if neuroimaging findings in infants who undergo extracorporeal membrane oxygenation (ECMO) are predictive of developmental outcome. MATERIALS AND METHODS: At 1-2 years of age, 183 ECMO survivors (69 female, 114 male) underwent developmental examination. Neuroimaging studies obtained at time of ECMO were assigned a neuroimaging score. Neuroimaging findings were correlated with developmental outcome. RESULTS: Eighty-five infants had neuroimaging abnormalities. Development was normal in 105 infants, suspect in 37, and delayed in 41. Mean neuroimaging scores were significantly worse in survivors with delayed development (P < or = .0001). The sensitivity and specificity of normal neuroimaging findings in prediction of normal outcome were 65% and 63%, respectively. Survivors with nonhemorrhagic abnormalities had a higher risk of delayed development than did those with isolated hemorrhagic abnormalities (39% vs 21%). CONCLUSION: Although they cannot be used alone to predict outcome, early neuroimaging scores can be used to assign risk categories for developmental outcome.
Authors: F G Blankenberg; N N Loh; P Bracci; H E D'Arceuil; W D Rhine; A M Norbash; B Lane; A Berg; B Person; M Coutant; D R Enzmann Journal: AJNR Am J Neuroradiol Date: 2000-01 Impact factor: 3.825
Authors: M A Wien; M T Whitehead; D Bulas; M Ridore; L Melbourne; G Oldenburg; B L Short; A N Massaro Journal: AJNR Am J Neuroradiol Date: 2017-02-16 Impact factor: 3.825
Authors: Maria W G Nijhuis-van der Sanden; Monique H M van der Cammen-van Zijp; Anjo J W M Janssen; Jolanda J C M Reuser; Petra Mazer; Arno F J van Heijst; Saskia J Gischler; Dick Tibboel; Louis A A Kollée Journal: Crit Care Date: 2009-04-02 Impact factor: 9.097
Authors: Hanneke IJsselstijn; Maayke Hunfeld; Raisa M Schiller; Robert J Houmes; Aparna Hoskote; Dick Tibboel; Arno F J van Heijst Journal: Front Pediatr Date: 2018-06-26 Impact factor: 3.418