Literature DB >> 7536724

Neuropeptides in the human penis: an immunohistochemical study.

C Hauser-Kronberger1, G W Hacker, A H Graf, D Mack, F Sundler, O Dietze, J Frick.   

Abstract

In the present study, the distribution of neuropeptides in the human penis is demonstrated by immunohistochemistry (IHC). IHC screening detected a complex network of nerve fibers containing vasoactive intestinal polypeptide (VIP), peptide histidine-methionine (PHM), prepro-VIP (111-122), neuropeptide Y (NPY), C-flanking peptide of NPY (C-PON), calcitonin gene-related peptide, substance P, and galanin immunoreactivities. Special attention was also given to the recently isolated, VIP-related lizard peptide helospectin, which could also be detected in neuronal elements in the penis. Colocalization studies showed the coexistence of VIP, PHM, and partly helospectin, and of NPY with C-PON within nerve fibers in the cavernous and spongious body, the glans penis, and the urethra.

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Year:  1994        PMID： 7536724

Source DB:  PubMed          Journal:  J Androl        ISSN： 0196-3635


  6 in total

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Review 2.  Neurotransmission and the contraction and relaxation of penile erectile tissues.

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Review 5.  Histological Correlates of Penile Sexual Sensation: Does Circumcision Make a Difference?

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Review 6.  The diversity of neuronal phenotypes in rodent and human autonomic ganglia.

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  6 in total

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