Literature DB >> 7536012

Apoptosis, Fas and systemic autoimmunity: the MRL-lpr/lpr model.

G G Singer1, A C Carrera, A Marshak-Rothstein, C Martínez, A K Abbas.   

Abstract

Proteins encoded by the fas and fas ligand (fasL) genes are involved in apoptotic cell death in lymphocytes. In this article we review the recent elucidation of the role of the Fas-FasL interactions in the maintenance of tolerance to self antigens and in the homeostatic regulation of lymphocyte clonal expansion, and discuss the mechanisms of autoimmunity in Fas- and FasL-deficient mutant mouse strains.

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Year:  1994        PMID： 7536012     DOI： 10.1016/0952-7915(94)90013-2

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  40 in total

Review 1.  Dominant regulation: a common mechanism of monoclonal antibody induced tolerance?

Authors:  K Honey; S P Cobbold; H Waldmann
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

Review 2.  Apoptosis.

Authors:  S Afford; S Randhawa
Journal:  Mol Pathol       Date:  2000-04

Review 3.  PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.

Authors:  Myung-Ja Kwon; Ruiqing Wang; Jian Ma; Zuoming Sun
Journal:  Endocr Metab Immune Disord Drug Targets       Date:  2010-12       Impact factor: 2.895

4.  Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS).

Authors:  David T Teachey; Dana A Obzut; Kelly Axsom; John K Choi; Kelly C Goldsmith; Junior Hall; Jessica Hulitt; Catherine S Manno; John M Maris; Nicholas Rhodin; Kathleen E Sullivan; Valerie I Brown; Stephan A Grupp
Journal:  Blood       Date:  2006-06-06       Impact factor: 22.113

Review 5.  Neuroimmunopathology in a murine model of neuropsychiatric lupus.

Authors:  David A Ballok
Journal:  Brain Res Rev       Date:  2006-12-20

6.  Differential ability of T cell subsets to undergo activation-induced cell death.

Authors:  A S Varadhachary; S N Perdow; C Hu; M Ramanarayanan; P Salgame
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-27       Impact factor: 11.205

7.  Mechanisms of Mycobacterium avium-induced resistance against insulin-dependent diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice: role of Fas and Th1 cells.

Authors:  T C Martins; A P Aguas
Journal:  Clin Exp Immunol       Date:  1999-02       Impact factor: 4.330

Review 8.  Immunosuppressive therapy for autoimmune inner ear disease.

Authors:  Maria C Buniel; Katie Geelan-Hansen; Peter C Weber; Vincent K Tuohy
Journal:  Immunotherapy       Date:  2009-05       Impact factor: 4.196

9.  Identification of gp96 as a novel target for treatment of autoimmune disease in mice.

Authors:  Jung Min Han; Nam Hoon Kwon; Jin Young Lee; Seung Jae Jeong; Hee Jung Jung; Hyeong Rae Kim; Zihai Li; Sunghoon Kim
Journal:  PLoS One       Date:  2010-03-23       Impact factor: 3.240

10.  TRAIL death receptor-4, decoy receptor-1 and decoy receptor-2 expression on CD8+ T cells correlate with the disease severity in patients with rheumatoid arthritis.

Authors:  Atil Bisgin; Ender Terzioglu; Cigdem Aydin; Burcak Yoldas; Veli Yazisiz; Nilufer Balci; Huseyin Bagci; Reginald M Gorczynski; Cezmi A Akdis; Salih Sanlioglu
Journal:  BMC Musculoskelet Disord       Date:  2010-08-27       Impact factor: 2.362
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