Literature DB >> 7535487

Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications.

A Mansour1, C A Fox, H Akil, S J Watson.   

Abstract

The cloning of the opioid receptors has profoundly affected our understanding of opioid-receptor expression, regulation and function. This review focuses on the impact that cloning has had on our understanding of opioid-receptor anatomy, and provides broad anatomical maps of the three opioid-receptor mRNAs in relation to their binding sites. In addition, three model anatomical systems, the nigrostriatal and mesolimbic dopamine systems, the hypothalamic neuroendocrine axes, and the ascending and descending pain pathways, have been highlighted to discuss issues of receptor transport, trafficking and pre- versus postsynaptic localization.

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Year:  1995        PMID： 7535487     DOI： 10.1016/0166-2236(95)93946-u

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  267 in total

1.  Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.

Authors:  J J Rodriguez; K Mackie; V M Pickel
Journal:  J Neurosci       Date:  2001-02-01       Impact factor: 6.167

2.  Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord.

Authors:  T Kohno; E Kumamoto; H Higashi; K Shimoji; M Yoshimura
Journal:  J Physiol       Date:  1999-08-01       Impact factor: 5.182

3.  The enigma of morphine tolerance: recent insights.

Authors:  S B Ray; S Wadhwa
Journal:  J Biosci       Date:  2001-12       Impact factor: 1.826

4.  Functional interaction between opioid and cannabinoid receptors in drug self-administration.

Authors:  M Navarro; M R Carrera; W Fratta; O Valverde; G Cossu; L Fattore; J A Chowen; R Gomez; I del Arco; M A Villanua; R Maldonado; G F Koob; F Rodriguez de Fonseca
Journal:  J Neurosci       Date:  2001-07-15       Impact factor: 6.167

5.  DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles.

Authors:  S J Evans; P V Choudary; M P Vawter; J Li; J H Meador-Woodruff; J F Lopez; S M Burke; R C Thompson; R M Myers; E G Jones; W E Bunney; S J Watson; H Akil
Journal:  Neurobiol Dis       Date:  2003-11       Impact factor: 5.996

Review 6.  CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention.

Authors:  Karl-Erik Andersson; Rikard Pehrson
Journal:  Drugs       Date:  2003       Impact factor: 9.546

7.  Augmented responses to morphine and cocaine in mice with a 12-lipoxygenase gene disruption.

Authors:  Carrie L Walters; Bao-Cheng Wang; Misty Godfrey; Duxin Sun; Colin D Funk; Julie A Blendy
Journal:  Psychopharmacology (Berl)       Date:  2003-07-04       Impact factor: 4.530

8.  GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area.

Authors:  Yanzhong Guan; Cheng Xiao; Kresimir Krnjevic; Guiqin Xie; Wanhong Zuo; Jiang-Hong Ye
Journal:  J Pharmacol Exp Ther       Date:  2011-12-30       Impact factor: 4.030

9.  Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats.

Authors:  Emily M Jutkiewicz; Nicholas P Walker; John E Folk; Kenner C Rice; Philip S Portoghese; James H Woods; John R Traynor
Journal:  J Pharmacol Exp Ther       Date:  2004-12-01       Impact factor: 4.030

10.  Translation of structure-activity relationships from cyclic mixed efficacy opioid peptides to linear analogues.

Authors:  Jessica P Anand; Vanessa R Porter-Barrus; Helen V Waldschmidt; Larisa Yeomans; Irina D Pogozheva; John R Traynor; Henry I Mosberg
Journal:  Biopolymers       Date:  2014-01       Impact factor: 2.505
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