Literature DB >> 7535247

The nitric oxide donors, azide and hydroxylamine, inhibit the programmed cell death of cytokine-deprived human eosinophils.

F Beauvais1, L Michel, L Dubertret.   

Abstract

Azide and hydroxylamine release nitric oxide (NO) enzymatically in biological conditions. We observed that both compounds were able to inhibit in vitro the programmed cell death of human eosinophils from peripheral blood. This protective effect could be mimicked by permeable cGMP analogs and by the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine. Moreover, the soluble guanylate cyclase inhibitor LY-83583 inhibited in a dose-response manner the effects of the NO donors. Consequently, via the increase of eosinophil survival, NO could contribute to the amplification of inflammatory and allergic processes. This effect appears to be mediated, at least in part, by the soluble guanylate pathway.

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Year:  1995        PMID： 7535247     DOI： 10.1016/0014-5793(95)00188-f

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  18 in total

1.  Nitric oxide at a low concentration protects murine macrophage RAW264 cells against nitric oxide-induced death via cGMP signaling pathway.

Authors:  Y Yoshioka; A Yamamuro; S Maeda
Journal:  Br J Pharmacol       Date:  2003-05       Impact factor: 8.739

2.  Endogenous nitric oxide activation protects against cigarette smoking induced apoptosis in endothelial cells.

Authors:  Muthuswamy Raveendran; Jing Wang; Duraisamy Senthil; Jian Wang; Budi Utama; Ying Shen; Donald Dudley; Yun Zhang; Xing Li Wang
Journal:  FEBS Lett       Date:  2005-01-31       Impact factor: 4.124

3.  Neutralization of B. anthracis toxins during ex vivo phagocytosis.

Authors:  Olga Tarasenko; Ashley Scott; April Jones; Lee Soderberg; Pierre Alusta
Journal:  Glycoconj J       Date:  2012-09-15       Impact factor: 2.916

4.  Glycoconjugates prevent B. anthracis toxin-induced cell death through binding while activating macrophages.

Authors:  Olga Tarasenko; Ashley Scott; Lee Soderberg; Pierre Alusta
Journal:  Glycoconj J       Date:  2011-12-02       Impact factor: 2.916

5.  Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling.

Authors:  Y M Kim; H T Chung; S S Kim; J A Han; Y M Yoo; K M Kim; G H Lee; H Y Yun; A Green; J Li; R L Simmons; T R Billiar
Journal:  J Neurosci       Date:  1999-08-15       Impact factor: 6.167

6.  Tumor necrosis factor-alpha plus actinomycin D-induced apoptosis of L929 cells is prevented by nitric oxide.

Authors:  S Hakoda; H Ishikura; N Takeyama; T Tanaka
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

7.  Stimulation of the cAMP pathway protects cultured cerebellar granule neurons against alcohol-induced cell death by activating the neuronal nitric oxide synthase (nNOS) gene.

Authors:  Bahri Karaçay; Guiying Li; Nicholas J Pantazis; Daniel J Bonthius
Journal:  Brain Res       Date:  2007-01-25       Impact factor: 3.252

8.  Polymeric glycoconjugates protect and activate macrophages to promote killing of Bacillus cereus spores during phagocytosis.

Authors:  Olga Tarasenko; Elizabeth Burton; Lee Soderberg; Pierre Alusta
Journal:  Glycoconj J       Date:  2008-01-17       Impact factor: 2.916

9.  Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.

Authors:  Sara M Thomazzi; Juliana Moreira; Sisi Marcondes; Gilberto De Nucci; Edson Antunes
Journal:  Br J Pharmacol       Date:  2004-01-26       Impact factor: 8.739

10.  Immunohistochemical approach reveals involvement of inducible nitric oxide synthase in rat late development.

Authors:  W F Zambuzzi; K B S Paiva; A C Batista; V S Lara; J M Granjeiro
Journal:  J Mol Histol       Date:  2009-07-09       Impact factor: 2.611
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