Literature DB >> 7534113

Amplification of the MET gene in glioma.

U Fischer1, H W Müller, H P Sattler, K Feiden, K D Zang, E Meese.   

Abstract

We have previously reported the finding of MET amplification linked to double minutes (dmins) in a human glioblastoma (TX3095). Because dmins are found in approximately 50% of glioblastomas, 18 gliomas were analyzed for MET amplification. Three grade IV glioblastomas and one grade II astrocytoma showed amplification. We could also localize the MET amplicon to dmins in glioblastoma TX3095 by fluorescence in situ hybridization.

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Mesh：

Year:  1995        PMID： 7534113     DOI： 10.1002/gcc.2870120111

Source DB:  PubMed          Journal:  Genes Chromosomes Cancer        ISSN： 1045-2257            Impact factor:   5.006


  13 in total

Review 1.  Studying a complex tumor: potential and pitfalls.

Authors:  Siyuan Zheng; Milan G Chheda; Roel G W Verhaak
Journal:  Cancer J       Date:  2012 Jan-Feb       Impact factor: 3.360

2.  Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors.

Authors:  V Wallenius; M Hisaoka; K Helou; G Levan; N Mandahl; J M Meis-Kindblom; L G Kindblom; J O Jansson
Journal:  Am J Pathol       Date:  2000-03       Impact factor: 4.307

3.  Phase I Study of AMG 337, a Highly Selective Small-molecule MET Inhibitor, in Patients with Advanced Solid Tumors.

Authors:  David S Hong; Patricia LoRusso; Omid Hamid; Filip Janku; Muaiad Kittaneh; Daniel V T Catenacci; Emily Chan; Tanios Bekaii-Saab; Shirish M Gadgeel; Robert D Loberg; Benny M Amore; Yuying C Hwang; Rui Tang; Gataree Ngarmchamnanrith; Eunice L Kwak
Journal:  Clin Cancer Res       Date:  2018-11-13       Impact factor: 12.531

4.  Detrended fluctuation analysis of genome-wide copy number profiles of glioblastomas using array-based comparative genomic hybridization.

Authors:  Yukiko Nakahara; Tetsuya Shiraishi; Hiroaki Okamoto; Toshihiro Mineta; Tsuyoshi Oishi; Kohsuke Sasaki; Kazuo Tabuchi
Journal:  Neuro Oncol       Date:  2004-10       Impact factor: 12.300

5.  Cytogenetic analysis of paediatric astrocytoma using comparative genomic hybridisation and fluorescence in-situ hybridisation.

Authors:  Samantha J Ward; Katherine Karakoula; Kim P Phipps; William Harkness; Richard Hayward; Dominic Thompson; Thomas S Jacques; Brian Harding; John L Darling; David G T Thomas; Tracy J Warr
Journal:  J Neurooncol       Date:  2010-01-06       Impact factor: 4.130

6.  Gene amplification is a poor prognostic factor in anaplastic oligodendrogliomas.

Authors:  Ahmed Idbaih; Emmanuelle Crinière; Yannick Marie; Audrey Rousseau; Karima Mokhtari; Michèle Kujas; Younas El Houfi; Catherine Carpentier; Sophie Paris; Blandine Boisselier; Florence Laigle-Donadey; Joëlle Thillet; Marc Sanson; Khê Hoang-Xuan; Jean-Yves Delattre
Journal:  Neuro Oncol       Date:  2008-06-10       Impact factor: 12.300

7.  Molecular cytogenetic analysis of 11 new breast cancer cell lines.

Authors:  F Forozan; R Veldman; C A Ammerman; N Z Parsa; A Kallioniemi; O P Kallioniemi; S P Ethier
Journal:  Br J Cancer       Date:  1999-12       Impact factor: 7.640

8.  IL-6 gene amplification and expression in human glioblastomas.

Authors:  A Tchirkov; C Rolhion; S Bertrand; J F Doré; J J Dubost; P Verrelle
Journal:  Br J Cancer       Date:  2001-08-17       Impact factor: 7.640

9.  Activating MET kinase rearrangements in melanoma and Spitz tumours.

Authors:  Iwei Yeh; Thomas Botton; Eric Talevich; A Hunter Shain; Alyssa J Sparatta; Arnaud de la Fouchardiere; Thaddeus W Mully; Jeffrey P North; Maria C Garrido; Alexander Gagnon; Swapna S Vemula; Timothy H McCalmont; Philip E LeBoit; Boris C Bastian
Journal:  Nat Commun       Date:  2015-05-27       Impact factor: 14.919

10.  A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.

Authors:  Beatrice S Knudsen; Ping Zhao; James Resau; Sandra Cottingham; Ermanno Gherardi; Eric Xu; Bree Berghuis; Jennifer Daugherty; Tessa Grabinski; Jose Toro; Troy Giambernardi; R Scot Skinner; Milton Gross; Eric Hudson; Eric Kort; Ernst Lengyel; Aviva Ventura; Richard A West; Qian Xie; Rick Hay; George Vande Woude; Brian Cao
Journal:  Appl Immunohistochem Mol Morphol       Date:  2009-01
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