Literature DB >> 75341

Hyperinsulinism, diabetes mellitus, and respiratory distress of the newborn: A common link?

W A Stubbs, S M Stubbs.   

Abstract

Hyperinsulinism may reduce glycerol-3-phosphate and dihydroxyacetone phosphate production and thus impair phospholipid synthesis and surfactant production in the lung. This mechanism could be responsible for the increased incidence of respiratory-distress syndrome in the infants of diabetic mothers.

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Year:  1978        PMID： 75341     DOI： 10.1016/s0140-6736(78)90075-2

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  4 in total

1.  Congenital malformations and blood glucose control in diabetic pregnancy.

Authors:  P J Watkins
Journal:  Br Med J (Clin Res Ed)       Date:  1982-05-08

2.  Chronic hyperglycemia reduces surface active material flux in tracheal fluid of fetal lambs.

Authors:  D Warburton
Journal:  J Clin Invest       Date:  1983-03       Impact factor: 14.808

3.  The influence of insulin on the lipids in the pulmonary artery and the lungs of severely diabetic rats. A histochemical and chemical study.

Authors:  A Reinilä; H K Akerblom; V A Koivisto
Journal:  Diabetologia       Date:  1979-01       Impact factor: 10.122

4.  Chronic hyperglycemia with secondary hyperinsulinemia inhibits the maturational response of fetal lamb lungs to cortisol.

Authors:  D Warburton
Journal:  J Clin Invest       Date:  1983-08       Impact factor: 14.808
  4 in total

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