Literature DB >> 7534085

Immunologically ignorant autoreactive T cells, epitope spreading and repertoire limitation.

C J Elson1, R N Barker, S J Thompson, N A Williams.   

Abstract

The factors that may cause antigen-presenting cells to alter the pattern of protein processing and presentation to autoreactive T cells, and thereby stimulate autoimmune disease, are currently under debate. In this article, Chris Elson and colleagues suggest that cytokines associated with T helper 1 (Th1) cells alter the processing of proteins and that this effect can be counteracted by Th2-associated cytokines.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7534085     DOI： 10.1016/0167-5699(95)80091-3

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  22 in total

1.  Healthy individuals have Goodpasture autoantigen-reactive T cells.

Authors:  Juan Zou; Sigrid Hannier; Lindsay S Cairns; Robert N Barker; Andrew J Rees; A Neil Turner; Richard G Phelps
Journal:  J Am Soc Nephrol       Date:  2008-01-23       Impact factor: 10.121

2.  DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state.

Authors:  M Mancini; M Hadchouel; H L Davis; R G Whalen; P Tiollais; M L Michel
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-29       Impact factor: 11.205

Review 3.  Relationship of extraintestinal involvements in inflammatory bowel disease: new insights into autoimmune pathogenesis.

Authors:  K M Das
Journal:  Dig Dis Sci       Date:  1999-01       Impact factor: 3.199

4.  The Th1-Th2 model--what relevance to inflammatory arthritis?

Authors:  P D Kiely
Journal:  Ann Rheum Dis       Date:  1998-06       Impact factor: 19.103

5.  Pristane-induced arthritis is CD4+ T-cell dependent.

Authors:  L M Stasiuk; M Ghoraishian; C J Elson; S J Thompson
Journal:  Immunology       Date:  1997-01       Impact factor: 7.397

Review 6.  Virus-induced immunopathology.

Authors:  B T Rouse
Journal:  Adv Virus Res       Date:  1996       Impact factor: 9.937

7.  The route of administration of an immunodominant peptide derived from heat-shock protein 65 dramatically affects disease outcome in pristane-induced arthritis.

Authors:  J N Francis; A G Lamont; S J Thompson
Journal:  Immunology       Date:  2000-03       Impact factor: 7.397

8.  Macrophages activated by Listeria monocytogenes induce organ-specific autoimmunity.

Authors:  K H Sonoda; G Matsuzaki; A Nomura; H Yamada; S Hamano; T Nakamura; A Mukasa; K Nomoto
Journal:  Immunology       Date:  1997-10       Impact factor: 7.397

9.  Production of the effector cytokine interleukin-17, rather than interferon-γ, is more strongly associated with autoimmune hemolytic anemia.

Authors:  Andrew M Hall; Omar M Zamzami; Natasha Whibley; Daniel P Hampsey; Anne M Haggart; Mark A Vickers; Robert N Barker
Journal:  Haematologica       Date:  2012-03-14       Impact factor: 9.941

10.  Persistent allopeptide reactivity and epitope spreading in chronic rejection of organ allografts.

Authors:  R Ciubotariu; Z Liu; A I Colovai; E Ho; S Itescu; S Ravalli; M A Hardy; R Cortesini; E A Rose; N Suciu-Foca
Journal:  J Clin Invest       Date:  1998-01-15       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.