Literature DB >> 7533138

Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity.

P H Jakobsen1, S Morris-Jones, A Rønn, L Hviid, T G Theander, I M Elhassan, I C Bygbjerg, B M Greenwood.   

Abstract

Increased serum concentrations of soluble intercellular adhesion molecule-1 (sICAM-1), soluble endothelial leucocyte adhesion molecule-1 (sELAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) were detected in Danish malaria patients infected with sequestering Plasmodium falciparum or non-sequestering P. vivax parasites, as well as in patients with sepsis or meningitis. Levels of soluble adhesion molecules remained elevated in the P. falciparum patients for several weeks after initiation of treatment. Plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 were higher in Gambian children with severe P. falciparum malaria than in children with mild malaria. Plasma levels of sVCAM-1 and sELAM-1 were significantly correlated. Plasma levels of sELAM-1 and sVCAM-1 may reflect endothelial inflammatory reactions and these reactions may be harmful for humans infected with malaria parasites.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7533138      PMCID： PMC1415057     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  24 in total

1.  Increased levels of released interleukin-2 receptors in Plasmodium falciparum malaria.

Authors:  P Nguyen-Dinh; A E Greenberg
Journal:  J Infect Dis       Date:  1988-12       Impact factor: 5.226

2.  Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum.

Authors:  A R Berendt; D L Simmons; J Tansey; C I Newbold; K Marsh
Journal:  Nature       Date:  1989-09-07       Impact factor: 49.962

3.  Molecular basis of sequestration in severe and uncomplicated Plasmodium falciparum malaria: differential adhesion of infected erythrocytes to CD36 and ICAM-1.

Authors:  C F Ockenhouse; M Ho; N N Tandon; G A Van Seventer; S Shaw; N J White; G A Jamieson; J D Chulay; H K Webster
Journal:  J Infect Dis       Date:  1991-07       Impact factor: 5.226

4.  Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.

Authors:  G G MacPherson; M J Warrell; N J White; S Looareesuwan; D A Warrell
Journal:  Am J Pathol       Date:  1985-06       Impact factor: 4.307

5.  Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria.

Authors:  P H Jakobsen; S Morris-Jones; T G Theander; L Hviid; M B Hansen; K Bendtzen; R G Ridley; B M Greenwood
Journal:  Clin Exp Immunol       Date:  1994-04       Impact factor: 4.330

6.  Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease.

Authors:  A Waage; A Halstensen; T Espevik
Journal:  Lancet       Date:  1987-02-14       Impact factor: 79.321

7.  TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria.

Authors:  D Kwiatkowski; A V Hill; I Sambou; P Twumasi; J Castracane; K R Manogue; A Cerami; D R Brewster; B M Greenwood
Journal:  Lancet       Date:  1990-11-17       Impact factor: 79.321

8.  Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies.

Authors:  J Carlson; H Helmby; A V Hill; D Brewster; B M Greenwood; M Wahlgren
Journal:  Lancet       Date:  1990-12-15       Impact factor: 79.321

9.  Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.

Authors:  L Osborn; C Hession; R Tizard; C Vassallo; S Luhowskyj; G Chi-Rosso; R Lobb
Journal:  Cell       Date:  1989-12-22       Impact factor: 41.582

10.  Tumor necrosis factor and disease severity in children with falciparum malaria.

Authors:  G E Grau; T E Taylor; M E Molyneux; J J Wirima; P Vassalli; M Hommel; P H Lambert
Journal:  N Engl J Med       Date:  1989-06-15       Impact factor: 91.245
View more
  34 in total

1.  Soluble platelet selectin (sP-selectin) and soluble vascular cell adhesion molecule-1 (sVCAM-1) decrease during therapy with benznidazole in children with indeterminate form of Chagas' disease.

Authors:  S A Laucella; E L Segura; A Riarte; E S Sosa
Journal:  Clin Exp Immunol       Date:  1999-12       Impact factor: 4.330

2.  Correlation between enhanced vascular permeability, up-regulation of cellular adhesion molecules and monocyte adhesion to the endothelium in the retina during the development of fatal murine cerebral malaria.

Authors:  N Ma; N H Hunt; M C Madigan; T Chan-Ling
Journal:  Am J Pathol       Date:  1996-11       Impact factor: 4.307

3.  The gamma/delta T-cell response to Plasmodium falciparum malaria in a population in which malaria is endemic.

Authors:  L Hviid; J A Kurtzhals; D Dodoo; O Rodrigues; A Rønn; J O Commey; F K Nkrumah; T G Theander
Journal:  Infect Immun       Date:  1996-10       Impact factor: 3.441

4.  Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria: a retrospective case-control study*.

Authors:  Andrea L Conroy; Simon J Glover; Michael Hawkes; Laura K Erdman; Karl B Seydel; Terrie E Taylor; Malcolm E Molyneux; Kevin C Kain
Journal:  Crit Care Med       Date:  2012-03       Impact factor: 7.598

5.  Modulation of experimental blood stage malaria through blockade of the B7/CD28 T-cell costimulatory pathway.

Authors:  A W Taylor-Robinson; E C Smith
Journal:  Immunology       Date:  1999-03       Impact factor: 7.397

6.  Membrane compartmentalization in Southeast Asian ovalocytosis red blood cells.

Authors:  Rossen Mirchev; Alexander Lam; David E Golan
Journal:  Br J Haematol       Date:  2011-07-27       Impact factor: 6.998

7.  Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria.

Authors:  Tsin W Yeo; Daniel A Lampah; Retno Gitawati; Emiliana Tjitra; Enny Kenangalem; Kim Piera; Ric N Price; Stephen B Duffull; David S Celermajer; Nicholas M Anstey
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-28       Impact factor: 11.205

8.  Systemic endothelial activation occurs in both mild and severe malaria. Correlating dermal microvascular endothelial cell phenotype and soluble cell adhesion molecules with disease severity.

Authors:  G D Turner; V C Ly; T H Nguyen; T H Tran; H P Nguyen; D Bethell; S Wyllie; K Louwrier; S B Fox; K C Gatter; N P Day; T H Tran; N J White; A R Berendt
Journal:  Am J Pathol       Date:  1998-06       Impact factor: 4.307

9.  Inflammatory reactions in placental blood of Plasmodium falciparum-infected women and high concentrations of soluble E-selectin and a circulating P. falciparum protein in the cord sera.

Authors:  P H Jakobsen; F N Rasheed; J N Bulmer; M Theisen; R G Ridley; B M Greenwood
Journal:  Immunology       Date:  1998-02       Impact factor: 7.397

10.  Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children.

Authors:  Fiona E Lovegrove; Noppadon Tangpukdee; Robert O Opoka; Erin I Lafferty; Nimerta Rajwans; Michael Hawkes; Srivicha Krudsood; Sornchai Looareesuwan; Chandy C John; W Conrad Liles; Kevin C Kain
Journal:  PLoS One       Date:  2009-03-20       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.