| Literature DB >> 7533053 |
Abstract
Traditional antipsychotic medications have targeted the dopamine system. Yet, the isolation and cloning of multiple dopamine receptor subtypes and the recognition of non-dopaminergic pathways (for example, serotonin) in schizophrenia have led to the development of new pharmacological strategies in pharmacotherapy. The author summarizes recent biochemical and pharmacological data and the clinical experience with novel antischizophrenic compounds.Entities:
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Year: 1994 PMID: 7533053
Source DB: PubMed Journal: Can J Psychiatry ISSN: 0706-7437 Impact factor: 4.356