Literature DB >> 7533053

Pharmacotherapy of schizophrenia: a review.

H K Sigmundson1.   

Abstract

Traditional antipsychotic medications have targeted the dopamine system. Yet, the isolation and cloning of multiple dopamine receptor subtypes and the recognition of non-dopaminergic pathways (for example, serotonin) in schizophrenia have led to the development of new pharmacological strategies in pharmacotherapy. The author summarizes recent biochemical and pharmacological data and the clinical experience with novel antischizophrenic compounds.

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Year:  1994        PMID: 7533053

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  3 in total

Review 1.  The Canadian experience with risperidone for the treatment of schizophrenia: an overview.

Authors:  M Iskedjian; M Hux; G J Remington
Journal:  J Psychiatry Neurosci       Date:  1998-09       Impact factor: 6.186

2.  Guanosine ameliorates positive symptoms of schizophrenia via modulating 5-HT1A and 5-HT2A receptors.

Authors:  Yu Mao; Yao Xing; Jie Li; Dong Dong; Shoude Zhang; Zhenjiang Zhao; Jingli Xie; Rui Wang; Honglin Li
Journal:  Am J Transl Res       Date:  2021-05-15       Impact factor: 4.060

3.  Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients.

Authors:  Y T Kwak; M S Koo; C H Choi; I Sunwoo
Journal:  BMC Med Genet       Date:  2001-03-05       Impact factor: 2.103

  3 in total

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