Literature DB >> 7532467

Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines.

H Yu1, E P Diamandis, N Zarghami, L Grass.   

Abstract

We demonstrate that the steroid hormone receptor-positive breast carcinoma cell lines T-47D and MCF-7 can be induced by androgens, progestins, mineralocorticosteroids, glucocorticosteroids, and antiestrogens, to produce prostate specific antigen (PSA). Estrogens failed to induce such stimulation in both cell lines and, in addition, were able to block the induction by androgens in the cell line T-47D. These data support and extend our previous report on PSA production by breast tumors and describe an in vitro system which can be used to study the phenomenon for possible application in prognosis and design of new therapy.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7532467     DOI： 10.1007/bf00666006

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  14 in total

Review 1.  Gene regulation by steroid hormones.

Authors:  M Beato
Journal:  Cell       Date:  1989-02-10       Impact factor: 41.582

2.  Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and growth factors.

Authors:  L D Read; G L Greene; B S Katzenellenbogen
Journal:  Mol Endocrinol       Date:  1989-02

3.  Steroid hormone receptor gene expression in human breast cancer cells: inverse relationship between oestrogen and glucocorticoid receptor messenger RNA levels.

Authors:  R E Hall; C S Lee; I E Alexander; J Shine; C L Clarke; R L Sutherland
Journal:  Int J Cancer       Date:  1990-12-15       Impact factor: 7.396

4.  Improved measurement of androgen receptors in human breast cancer.

Authors:  O A Lea; S Kvinnsland; T Thorsen
Journal:  Cancer Res       Date:  1989-12-15       Impact factor: 12.701

Review 5.  Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate.

Authors:  J E Oesterling
Journal:  J Urol       Date:  1991-05       Impact factor: 7.450

6.  Prostate marker immunoreactivity in salivary gland neoplasms. A rare pitfall in immunohistochemistry.

Authors:  J H van Krieken
Journal:  Am J Surg Pathol       Date:  1993-04       Impact factor: 6.394

7.  Ultrasensitive time-resolved immunofluorometric assay of prostate-specific antigen in serum and preliminary clinical studies.

Authors:  H Yu; E P Diamandis
Journal:  Clin Chem       Date:  1993-10       Impact factor: 8.327

8.  In vitro measurement of cytosol and cell nuclear androgen receptors in male rat brain and pituitary.

Authors:  M Y McGinnis; P G Davis; M J Meaney; M Singer; B S McEwen
Journal:  Brain Res       Date:  1983-09-19       Impact factor: 3.252

9.  Ligand-modulated regulation of progesterone receptor messenger ribonucleic acid and protein in human breast cancer cell lines.

Authors:  L D Read; C E Snider; J S Miller; G L Greene; B S Katzenellenbogen
Journal:  Mol Endocrinol       Date:  1988-03

10.  Ectopic production of prostate specific antigen by a breast tumor metastatic to the ovary.

Authors:  H Yu; E P Diamandis; M Levesque; P Sismondi; P Zola; D Katsaros
Journal:  J Clin Lab Anal       Date:  1994       Impact factor: 2.352
View more
  24 in total

1.  Prostate specific antigen in breast cancer, benign breast disease and normal breast tissue.

Authors:  H Yu; E P Diamandis; M Levesque; M Giai; R Roagna; R Ponzone; P Sismondi; M Monne; C M Croce
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

Review 2.  Putative functions of tissue kallikrein-related peptidases in vaginal fluid.

Authors:  Carla M J Muytjens; Stella K Vasiliou; Katerina Oikonomopoulou; Ioannis Prassas; Eleftherios P Diamandis
Journal:  Nat Rev Urol       Date:  2016-09-07       Impact factor: 14.432

3.  Serum complexed and free prostate-specific antigen (PSA) for the diagnosis of the polycystic ovarian syndrome (PCOS).

Authors:  Eleftherios P Diamandis; Frank Z Stanczyk; Sarah Wheeler; Anu Mathew; Martin Stengelin; Galina Nikolenko; Eli N Glezer; Marshall D Brown; Yingye Zheng; Yen-Hao Chen; Hsiao-Li Wu; Ricardo Azziz
Journal:  Clin Chem Lab Med       Date:  2017-10-26       Impact factor: 3.694

Review 4.  Reconnoitring the status of prostate specific antigen and its role in women.

Authors:  Prakruti Dash
Journal:  Indian J Clin Biochem       Date:  2014-06-22

5.  Free/Total Serum Prostate-Specific Antigen Ratio in Women with Colorectal Cancer Has Prognostic Significance.

Authors:  Nüvit Duraker; Zeynep Civelek Çaynak; Didem Can Trabulus
Journal:  J Gastrointest Cancer       Date:  2017-03

6.  Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer.

Authors:  Daniel L J Thorek; Anson T Ku; Nicholas Mitsiades; Darren Veach; Philip A Watson; Dipti Metha; Sven-Erik Strand; Sai Kiran Sharma; Jason S Lewis; Diane S Abou; Hans G Lilja; Steven M Larson; Michael R McDevitt; David Ulmert
Journal:  Clin Cancer Res       Date:  2018-09-25       Impact factor: 12.531

7.  Tissue prostate-specific antigen facilitates refractory prostate tumor progression via enhancing ARA70-regulated androgen receptor transactivation.

Authors:  Yuanjie Niu; Shuyuan Yeh; Hiroshi Miyamoto; Gonghui Li; Saleh Altuwaijri; Jianqun Yuan; Ruifa Han; Tengxiang Ma; Hann-Chorng Kuo; Chawnshang Chang
Journal:  Cancer Res       Date:  2008-09-01       Impact factor: 12.701

8.  Quantification of prostate-specific antigen immunoreactivity in human breast cyst fluids.

Authors:  F Mannello; G Bocchiotti; G Bianchi; F Marcheggiani; G Gazzanelli
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

9.  Prostate specific antigen--a new constituent of breast cyst fluid.

Authors:  E P Diamandis; H Yu; C López-Otín
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

10.  Diagnostic value of prostate-specific antigen (PSA) and free prostate specific antigen (fPSA) in women with ovulatory and anovulatory polycystic ovary syndrome.

Authors:  Kubilay UKINC; Halil Onder Ersoz; Cihangir Erem; Arif Bayram Hacihasanoglu
Journal:  Endocrine       Date:  2008-11-14       Impact factor: 3.633
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.