Literature DB >> 7532458

CD40 and its ligand in the regulation of humoral immunity.

S J Klaus1, I Berberich, G Shu, E A Clark.   

Abstract

T cells provide help for B cell antibody production by cell-cell contact and by soluble factors. CD40L is the predominant protein induced on activated T cells which constitutes contact-dependent help, and lack of CD40L or blocking CD40-CD40L interactions leads to severely impaired antibody production. In addition to CD40-CD40L, B and T cells express costimulatory, accessory molecules which amplify T and B cell function and allow for reciprocal dialogues during antigen presentation. Interactions between costimulatory counter-receptors can determine lymphocyte activation or nonresponsiveness, and provides a means for regulating self-tolerance.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7532458     DOI： 10.1006/smim.1994.1036

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  9 in total

Review 1.  Costimulation of Th17 cells: Adding fuel or putting out the fire in the inflamed gut?

Authors:  Zili Zhang; James T Rosenbaum; Wenwei Zhong; Carmen Lim; David J Hinrichs
Journal:  Semin Immunopathol       Date:  2010-01-30       Impact factor: 9.623

2.  A functional CD40 receptor is expressed in pancreatic beta cells.

Authors:  D Klein; F Barbé-Tuana; A Pugliese; H Ichii; D Garza; M Gonzalez; R D Molano; C Ricordi; R L Pastori
Journal:  Diabetologia       Date:  2005-02-03       Impact factor: 10.122

3.  Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation.

Authors:  Franziska Zabel; Antonia Fettelschoss; Monique Vogel; Pål Johansen; Thomas M Kündig; Martin F Bachmann
Journal:  Immunology       Date:  2017-01-05       Impact factor: 7.397

4.  Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice.

Authors:  Natalia V Giltiay; Yi Lu; Jaime L Cullen; Trine N Jørgensen; Mark J Shlomchik; Xiaoxia Li
Journal:  J Immunol       Date:  2013-07-31       Impact factor: 5.422

5.  Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases.

Authors:  I Berberich; G Shu; F Siebelt; J R Woodgett; J M Kyriakis; E A Clark
Journal:  EMBO J       Date:  1996-01-02       Impact factor: 11.598

6.  RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion.

Authors:  Caroline C Krueger; Franziska Thoms; Elsbeth Keller; Fabiana M S Leoratti; Monique Vogel; Martin F Bachmann
Journal:  Front Immunol       Date:  2019-04-05       Impact factor: 7.561

7.  Chronic Alcohol Exposure Among People Living with HIV Is Associated with Innate Immune Activation and Alterations in Monocyte Phenotype and Plasma Cytokine Profile.

Authors:  Michelle L Underwood; Byung Park; Luke S Uebelhoer; Geoffrey Gu; Lynn E Kunkel; Philip T Korthuis; Ryan R Cook; Rafick Pierre Sekaly; Susan Pereira Ribeiro; Christina L Lancioni
Journal:  Front Immunol       Date:  2022-03-18       Impact factor: 8.786

8.  The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer.

Authors:  Annette Torgunrud; Hanna Abrahamsson; Sebastian Meltzer; Arne Mide Solbakken; Kjersti Flatmark; Svein Dueland; Kine Mari Bakke; Paula Anna Bousquet; Anne Negård; Christin Johansen; Lars Gustav Lyckander; Finn Ole Larsen; Jakob Vasehus Schou; Kathrine Røe Redalen; Anne Hansen Ree
Journal:  Br J Cancer       Date:  2021-04-09       Impact factor: 7.640

Review 9.  The Costimulatory Pathways and T Regulatory Cells in Ischemia-Reperfusion Injury: A Strong Arm in the Inflammatory Response?

Authors:  Laura de Ramon; Jordi Guiteras; Roser Guiteras; Josep M Cruzado; Josep M Grinyó; Juan Torras
Journal:  Int J Mol Sci       Date:  2018-04-25       Impact factor: 5.923
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.