Literature DB >> 7532456

The expansive role of CD40 and its ligand, gp39, in immunity.

T M Foy1, F H Durie, R J Noelle.   

Abstract

The interactions between CD40 and its ligand, gp39, are central to the development and maintenance of immunity. The role this receptor-ligand pair plays in B cell activation, isotype switching and memory generation has been firmly established through the study of in vitro and in vivo murine models, as well as human in vitro systems and immunodeficiencies. In this review, the potential role of gp39 in the regulation of co-stimulatory molecules and their implications on thymic education and peripheral tolerance are discussed.

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Year:  1994        PMID： 7532456     DOI： 10.1006/smim.1994.1034

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  12 in total

Review 1.  Tropism of human pegivirus (formerly known as GB virus C/hepatitis G virus) and host immunomodulation: insights into a highly successful viral infection.

Authors:  Ernest T Chivero; Jack T Stapleton
Journal:  J Gen Virol       Date:  2015-02-09       Impact factor: 3.891

Review 2.  Molecular mechanism and function of CD40/CD40L engagement in the immune system.

Authors:  Raul Elgueta; Micah J Benson; Victor C de Vries; Anna Wasiuk; Yanxia Guo; Randolph J Noelle
Journal:  Immunol Rev       Date:  2009-05       Impact factor: 12.988

3.  Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice.

Authors:  G A Holländer; E Castigli; R Kulbacki; M Su; S J Burakoff; J C Gutierrez-Ramos; R S Geha
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

4.  Immunomodulatory effect of a plasmid expressing CD40 ligand on DNA vaccination against human immunodeficiency virus type-1.

Authors:  A Ihata; S Watabe; S Sasaki; A Shirai; J Fukushima; K Hamajima; J Inoue; K Okuda
Journal:  Immunology       Date:  1999-11       Impact factor: 7.397

Review 5.  Prevention of transplant rejection: current treatment guidelines and future developments.

Authors:  N Perico; G Remuzzi
Journal:  Drugs       Date:  1997-10       Impact factor: 9.546

6.  Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome.

Authors:  K Agematsu; H Nagumo; K Shinozaki; S Hokibara; K Yasui; K Terada; N Kawamura; T Toba; S Nonoyama; H D Ochs; A Komiyama
Journal:  J Clin Invest       Date:  1998-08-15       Impact factor: 14.808

Review 7.  B-cell-targeted therapies in systemic lupus erythematosus.

Authors:  Vera Sau-Fong Chan; Helen Hoi-Lun Tsang; Rachel Chun-Yee Tam; Liwei Lu; Chak-Sing Lau
Journal:  Cell Mol Immunol       Date:  2013-01-28       Impact factor: 11.530

8.  CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection.

Authors:  P Borrow; D F Tough; D Eto; A Tishon; I S Grewal; J Sprent; R A Flavell; M B Oldstone
Journal:  J Virol       Date:  1998-09       Impact factor: 5.103

9.  C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer.

Authors:  Kosuke Sasaki; Shigetsugu Takano; Satoshi Tomizawa; Yoji Miyahara; Katsunori Furukawa; Tsukasa Takayashiki; Satoshi Kuboki; Mamoru Takada; Masayuki Ohtsuka
Journal:  J Exp Clin Cancer Res       Date:  2021-06-24

10.  A B cell receptor with two Igalpha cytoplasmic domains supports development of mature but anergic B cells.

Authors:  Amy Reichlin; Anna Gazumyan; Hitoshi Nagaoka; Kathrin H Kirsch; Manfred Kraus; Klaus Rajewsky; Michel C Nussenzweig
Journal:  J Exp Med       Date:  2004-03-15       Impact factor: 14.307
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