Literature DB >> 7532151

The gene coding for the B cell surface protein CD19 is localized on human chromosome 16p11.

P Stapleton1, Z Kozmik, A Weith, M Busslinger.   

Abstract

The CD19 gene codes for one of the earliest markers of the human B cell lineage and is a target for the B lymphoid-specific transcription factor BSAP (Pax-5). The transmembrane protein CD19 has been implicated in controlling proliferation of mature B lymphocytes by modulating signal transduction through the antigen receptor. In this study, we have employed Southern blot and fluorescence in situ hybridization analyses to localize the CD19 gene to human chromosome 16p11.

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Year:  1995        PMID: 7532151     DOI: 10.1007/bf00209407

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  19 in total

1.  CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.

Authors:  R H Carter; D T Fearon
Journal:  Science       Date:  1992-04-03       Impact factor: 47.728

2.  The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP.

Authors:  Z Kozmik; S Wang; P Dörfler; B Adams; M Busslinger
Journal:  Mol Cell Biol       Date:  1992-06       Impact factor: 4.272

3.  Antigen-independent regulation of cytoplasmic calcium in B cells with a 12-kDa B-cell growth factor and anti-CD19.

Authors:  J A Ledbetter; P S Rabinovitch; C H June; C W Song; E A Clark; F M Uckun
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

Review 4.  Integrating maps of chromosome 16.

Authors:  J C Mulley; G R Sutherland
Journal:  Curr Opin Genet Dev       Date:  1993-06       Impact factor: 5.578

5.  CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM.

Authors:  J P DiSanto; J Y Bonnefoy; J F Gauchat; A Fischer; G de Saint Basile
Journal:  Nature       Date:  1993-02-11       Impact factor: 49.962

6.  The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases.

Authors:  D Vetrie; I Vorechovský; P Sideras; J Holland; A Davies; F Flinter; L Hammarström; C Kinnon; R Levinsky; M Bobrow
Journal:  Nature       Date:  1993-01-21       Impact factor: 49.962

7.  Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

Authors:  B Adams; P Dörfler; A Aguzzi; Z Kozmik; P Urbánek; I Maurer-Fogy; M Busslinger
Journal:  Genes Dev       Date:  1992-09       Impact factor: 11.361

8.  Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia.

Authors:  S Tsukada; D C Saffran; D J Rawlings; O Parolini; R C Allen; I Klisak; R S Sparkes; H Kubagawa; T Mohandas; S Quan
Journal:  Cell       Date:  1993-01-29       Impact factor: 41.582

9.  CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein-Barr virus-related cytoplasmic tail.

Authors:  I Stamenkovic; B Seed
Journal:  J Exp Med       Date:  1988-09-01       Impact factor: 14.307

10.  Tyrosine phosphorylation of CD19 in pre-B and mature B cells.

Authors:  N J Chalupny; S B Kanner; G L Schieven; S F Wee; L K Gilliland; A Aruffo; J A Ledbetter
Journal:  EMBO J       Date:  1993-07       Impact factor: 11.598

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