Literature DB >> 7531334

The significance of CD44 in human pancreatic cancer: I. High expression of CD44 in human pancreatic adenocarcinoma.

M Takada1, M Yamamoto, Y Saitoh.   

Abstract

The CD44 cell surface glycoprotein, which is the adhesion molecule of lymphocytes, has been suggested to be an important factor for the metastatic potential and invasive ability of cancer. We demonstrated the expression of CD44 in human pancreatic adenocarcinoma cells and normal cells by using flow cytometry (FACS-can) and immunohistological staining. CD44 was highly expressed in human pancreatic adenocarcinoma cells, while it was little expressed in normal human pancreas cells. These results indicate that the quantitative analysis of CD44 expression may be a useful diagnostic tool for pancreatic cancer.

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Year:  1994        PMID: 7531334     DOI: 10.1097/00006676-199411000-00013

Source DB:  PubMed          Journal:  Pancreas        ISSN: 0885-3177            Impact factor:   3.327


  14 in total

Review 1.  CD44 and the adhesion of neoplastic cells.

Authors:  Z Rudzki; S Jothy
Journal:  Mol Pathol       Date:  1997-04

2.  Bioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkers.

Authors:  Randy S Haun; Charles M Quick; Eric R Siegel; Ilangovan Raju; Samuel G Mackintosh; Alan J Tackett
Journal:  Cancer Biol Ther       Date:  2015-07-15       Impact factor: 4.742

Review 3.  CD44 in inflammation and metastasis.

Authors:  J Lesley; R Hyman; N English; J B Catterall; G A Turner
Journal:  Glycoconj J       Date:  1997-08       Impact factor: 2.916

4.  CD44 exon 6 expression as a possible early prognostic factor in primary node negative breast carcinoma.

Authors:  N Guriec; L Marcellin; B Gairard; H Caldéroli; A Wilk; R Renaud; J P Bergerat; F Oberling
Journal:  Clin Exp Metastasis       Date:  1996-10       Impact factor: 5.150

5.  E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid.

Authors:  Daniel J Shea; Yi W Li; Kathleen J Stebe; Konstantinos Konstantopoulos
Journal:  FASEB J       Date:  2017-08-01       Impact factor: 5.191

6.  Establishment and characterization of human pancreatic carcinoma lines with a high metastatic potential in the liver of nude mice.

Authors:  T Shishido; T Yasoshima; K Hirata; R Denno; M Mukaiya; H Ura; K Yamaguchi; S Kawaguchi; N Sato
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

7.  Differential expression of CD44v6 in adenocarcinoma of the pancreas: an immunohistochemical study.

Authors:  E M Castellà; A Ariza; I Ojanguren; J L Mate; X Roca; A Fernández-Vasalo; J J Navas-Palacios
Journal:  Virchows Arch       Date:  1996-11       Impact factor: 4.064

Review 8.  Pancreatic adenocarcinoma: epidemiology and genetics.

Authors:  T Y Flanders; W D Foulkes
Journal:  J Med Genet       Date:  1996-11       Impact factor: 6.318

9.  CRABP-II is a highly sensitive and specific diagnostic molecular marker for pancreatic ductal adenocarcinoma in distinguishing from benign pancreatic conditions.

Authors:  Wenbin Xiao; Hong Hong; Amad Awadallah; Shuiliang Yu; Lan Zhou; Wei Xin
Journal:  Hum Pathol       Date:  2014-01-31       Impact factor: 3.466

10.  Transferrin Modified GSH Sensitive Hyaluronic Acid Derivative Micelle to Deliver HSP90 Inhibitors to Enhance the Therapeutic Efficacy of Brain Cancers.

Authors:  Tilahun Ayane Debele; Ping-Ching Wu; Yu-Feng Wei; Jian-Ying Chuang; Kwang-Yu Chang; Jui-Hung Tsai; Wen-Pin Su
Journal:  Cancers (Basel)       Date:  2021-05-14       Impact factor: 6.639

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