PURPOSE: To characterize the racial differences in prognostic factors and treatment outcome for patients undergoing radiation therapy for carcinoma of the prostate. MATERIALS AND METHODS: From January 1975 through December 1989, 489 white and 157 black men with carcinoma of the prostate underwent irradiation. Factors analyzed were patient age, tumor stage and grade, prostate-specific antigen (PSA) levels, and disease-control and survival rates. RESULTS: More black patients than white patients were found to have poorly differentiated tumors. Black patients had higher PSA levels before and after treatment, resulting in a higher distant failure rate and poorer overall, cause-specific, and disease-free survival rates. CONCLUSION: Black men have more aggressive prostatic tumors, a higher rate of metastasis, and a poorer survival rate than do white men.
PURPOSE: To characterize the racial differences in prognostic factors and treatment outcome for patients undergoing radiation therapy for carcinoma of the prostate. MATERIALS AND METHODS: From January 1975 through December 1989, 489 white and 157 black men with carcinoma of the prostate underwent irradiation. Factors analyzed were patient age, tumor stage and grade, prostate-specific antigen (PSA) levels, and disease-control and survival rates. RESULTS: More black patients than white patients were found to have poorly differentiated tumors. Black patients had higher PSA levels before and after treatment, resulting in a higher distant failure rate and poorer overall, cause-specific, and disease-free survival rates. CONCLUSION: Black men have more aggressive prostatic tumors, a higher rate of metastasis, and a poorer survival rate than do white men.
Authors: B K Hamilton; L Rybicki; M Sekeres; M Kalaycio; R Hanna; R Sobecks; R Dean; H Duong; B T Hill; B Bolwell; E Copelan Journal: Bone Marrow Transplant Date: 2015-03-23 Impact factor: 5.483
Authors: K Scott Baker; Stella M Davies; Navneet S Majhail; Anna Hassebroek; John P Klein; Karen K Ballen; Carolyn L Bigelow; Haydar A Frangoul; Cheryl L Hardy; Christopher Bredeson; Jason Dehn; Debra Friedman; Theresa Hahn; Gregory Hale; Hillard M Lazarus; C F LeMaistre; Fausto Loberiza; Dipnarine Maharaj; Philip McCarthy; Michelle Setterholm; Stephen Spellman; Michael Trigg; Richard T Maziarz; Galen Switzer; Stephanie J Lee; J Douglas Rizzo Journal: Biol Blood Marrow Transplant Date: 2009-09-25 Impact factor: 5.742