Literature DB >> 7529880

Chromosomal damages by ethanol and acetaldehyde in Saccharomyces cerevisiae as studied by pulsed field gel electrophoresis.

H Ristow1, A Seyfarth, E R Lochmann.   

Abstract

We report on the effect of ethanol and acetaldehyde on yeast chromosomal DNA and on isolated DNA. Ethanol induced DNA single-strand breaks in repair deficient but not in repair proficient Saccharomyces cerevisiae. Acetaldehyde has a deleterious effect on chromosomal DNA in cells as well as on isolated DNA. The results presented support earlier data to show that ethanol is mutagenic via its first metabolite, acetaldehyde.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7529880     DOI： 10.1016/0027-5107(94)00165-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  12 in total

1.  Analysis and dynamics of the chromosomal complements of wild sparkling-wine yeast strains.

Authors:  D Nadal; D Carro; J Fernández-Larrea; B Piña
Journal:  Appl Environ Microbiol       Date:  1999-04       Impact factor: 4.792

2.  Mitochondrial DNA loss caused by ethanol in Saccharomyces flor yeasts.

Authors:  J I Ibeas; J Jimenez
Journal:  Appl Environ Microbiol       Date:  1997-01       Impact factor: 4.792

3.  Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancer.

Authors:  Kala Visvanathan; Rosa M Crum; Paul T Strickland; Xiaojun You; Ingo Ruczinski; Sonja I Berndt; Anthony J Alberg; Sandra C Hoffman; George W Comstock; Douglas A Bell; Kathy J Helzlsouer
Journal:  Alcohol Clin Exp Res       Date:  2007-03       Impact factor: 3.455

4.  Alcohol Intake and Risk of Breast Cancer by Histologic Subtype and Estrogen Receptor Status Among Women Aged 55 to 74 Years.

Authors:  Michelle L Baglia; Kathleen E Malone; Mei-Tzu C Tang; Christopher I Li
Journal:  Horm Cancer       Date:  2017-05-31       Impact factor: 3.869

5.  Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.

Authors:  J P Visapää; K Götte; M Benesova; J Li; N Homann; C Conradt; H Inoue; M Tisch; K Hörrmann; S Väkeväinen; M Salaspuro; H K Seitz
Journal:  Gut       Date:  2004-06       Impact factor: 23.059

6.  Genetic analysis of apomictic wine yeasts.

Authors:  Francisco Castrejón; Enrique Martínez-Force; Tahía Benítez; Antonio C Codón
Journal:  Curr Genet       Date:  2004-02-04       Impact factor: 3.886

7.  Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast.

Authors:  Chiaki Noguchi; Grant Grothusen; Vinesh Anandarajan; Marta Martínez-Lage García; Daniel Terlecky; Krysten Corzo; Katsunori Tanaka; Hiroshi Nakagawa; Eishi Noguchi
Journal:  Cell Cycle       Date:  2016-09-29       Impact factor: 4.534

8.  Genome-wide amplifications caused by chromosomal rearrangements play a major role in the adaptive evolution of natural yeast.

Authors:  Juan J Infante; Kenneth M Dombek; Laureana Rebordinos; Jesús M Cantoral; Elton T Young
Journal:  Genetics       Date:  2003-12       Impact factor: 4.562

9.  Comparative polygenic analysis of maximal ethanol accumulation capacity and tolerance to high ethanol levels of cell proliferation in yeast.

Authors:  Thiago M Pais; María R Foulquié-Moreno; Georg Hubmann; Jorge Duitama; Steve Swinnen; Annelies Goovaerts; Yudi Yang; Françoise Dumortier; Johan M Thevelein
Journal:  PLoS Genet       Date:  2013-06-06       Impact factor: 5.917

10.  Strategy for adapting wine yeasts for bioethanol production.

Authors:  Beng Guat Ooi; Kevin R Lankford
Journal:  Int J Mol Sci       Date:  2009-01-26       Impact factor: 6.208
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.