| Literature DB >> 7529819 |
J D Palmer1, D A Francis, O S Roath, J L Francis, F Iannotti.
Abstract
A patient undergoing intracranial surgery developed disseminated intravascular coagulation with life threatening peroperative bleeding. Thromboelastography established the diagnosis of hyperfibrinolysis, usually a fatal complication of a neurosurgical operation. With the administration of a high dose regimen of aprotinin (Trasylol) the haemorrhage was controlled and the hyperfibrinolytic state reversed. Evaluation of blood samples from the jugular bulb suggested that there was a pronounced local release of tissue plasminogen activator into the circulation.Entities:
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Year: 1995 PMID： 7529819 PMCID： PMC1073281 DOI： 10.1136/jnnp.58.1.104
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154