Literature DB >> 7529196

Evaluation of indeterminate sera for hepatitis C virus by assays using synthetic peptides.

D Rivanera1, G Lorino, D Lilli, G Dicuonzo, C Mancini.   

Abstract

The development of new immunodiagnostic systems to study antibodies anti-HCV based on the use of synthetic peptides are potentially very important in the evaluation of indeterminate samples. We have compared two immunodiagnostic tests, the 3-RIBA and LIA-HCV test system, to examine the samples rated as indeterminate by the 2-RIBA test. The results showed that the specificity of the new tests has improved, in fact 29/40 of the indeterminate samples studied became positive with both tests. However, the 3-RIBA test showed higher sensitivity, since two samples negative by LIA-HCV, were positive with this system.

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Year:  1994        PMID: 7529196     DOI: 10.1007/bf01730378

Source DB:  PubMed          Journal:  Eur J Epidemiol        ISSN: 0393-2990            Impact factor:   8.082


  14 in total

1.  Detection of chronic hepatitis C virus infection by four diagnostic systems: first-generation and second-generation enzyme-linked immunosorbent assay, second-generation recombinant immunoblot assay and nested polymerase chain reaction analysis.

Authors:  Y Nakatsuji; A Matsumoto; E Tanaka; H Ogata; K Kiyosawa
Journal:  Hepatology       Date:  1992-08       Impact factor: 17.425

2.  Antibody to superoxide dismutase, autoimmune hepatitis, and antibody tests for hepatitis C virus.

Authors:  Y Ikeda; G Toda; N Hashimoto; K Kurokawa
Journal:  Lancet       Date:  1990-06-02       Impact factor: 79.321

3.  False-positive anti-HCV tests in rheumatoid arthritis.

Authors:  L Theilmann; M Blazek; T Goeser; K Gmelin; B Kommerell; W Fiehn
Journal:  Lancet       Date:  1990-06-02       Impact factor: 79.321

4.  False-positive hepatitis C virus antibody tests in paraproteinaemia.

Authors:  D Boudart; J C Lucas; J Y Muller; D Le Carrer; B Planchon; J L Harousseau
Journal:  Lancet       Date:  1990-07-07       Impact factor: 79.321

5.  Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.

Authors:  H J Alter; R H Purcell; J W Shih; J C Melpolder; M Houghton; Q L Choo; G Kuo
Journal:  N Engl J Med       Date:  1989-11-30       Impact factor: 91.245

Review 6.  Non-A, non-B hepatitis and the anti-HCV assay.

Authors:  J A Barbara; M Contreras
Journal:  Vox Sang       Date:  1991       Impact factor: 2.144

7.  Antibody to hepatitis C virus in post-transfusion hepatitis.

Authors:  F Tremolada; C Casarin; A Tagger; M L Ribero; G Realdi; A Alberti; A Ruol
Journal:  Ann Intern Med       Date:  1991-02-15       Impact factor: 25.391

8.  Prevalence of antibody to hepatitis C virus in hemodialysis patients.

Authors:  J Hayashi; K Nakashima; W Kajiyama; A Noguchi; M Morofuji; Y Maeda; S Kashiwagi
Journal:  Am J Epidemiol       Date:  1991-09-15       Impact factor: 4.897

9.  An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

Authors:  G Kuo; Q L Choo; H J Alter; G L Gitnick; A G Redeker; R H Purcell; T Miyamura; J L Dienstag; M J Alter; C E Stevens
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

10.  Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result?

Authors:  I G McFarlane; H M Smith; P J Johnson; G P Bray; D Vergani; R Williams
Journal:  Lancet       Date:  1990-03-31       Impact factor: 79.321

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