Literature DB >> 7528886

Establishment and validation of a dose-effect curve for gamma-rays by cytogenetic analysis.

J F Barquinero1, L Barrios, M R Caballín, R Miró, M Ribas, A Subias, J Egozcue.   

Abstract

A dose-effect curve obtained by analysis of dicentric chromosomes after irradiation of peripheral blood samples, from one donor, at 11 different doses of gamma-rays is presented. For the elaboration of this curve, more than 18,000 first division metaphases have been analyzed. The results fit very well to the linear-quadratic model. To validate the curve, samples from six individuals (three controls and three occupationally exposed persons) were irradiated at 2 Gy. The results obtained, when compared with the curve, showed that in all cases the 95% confidence interval included the 2 Gy dose, with estimated dose ranges from 1.82 to 2.19 Gy.

Entities:  

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Year:  1995        PMID： 7528886     DOI： 10.1016/0027-5107(94)00150-4

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  5 in total

1.  A Bayesian hierarchical method to account for random effects in cytogenetic dosimetry based on calibration curves.

Authors:  Shuhei Mano; Yumiko Suto
Journal:  Radiat Environ Biophys       Date:  2014-08-26       Impact factor: 1.925

2.  Dose-response curves for analyzing of dicentric chromosomes and chromosome translocations following doses of 1000 mGy or less, based on irradiated peripheral blood samples from five healthy individuals.

Authors:  Yu Abe; Mitsuaki A Yoshida; Kurumi Fujioka; Yumiko Kurosu; Risa Ujiie; Aki Yanagi; Naohiro Tsuyama; Tomisato Miura; Toshiya Inaba; Kenji Kamiya; Akira Sakai
Journal:  J Radiat Res       Date:  2018-01-01       Impact factor: 2.724

Review 3.  Estimation of the effects of medical diagnostic radiation exposure based on DNA damage.

Authors:  Lin Shi; Satoshi Tashiro
Journal:  J Radiat Res       Date:  2018-04-01       Impact factor: 2.724

4.  Development of Dose-Response Calibration Curve for Dicentric Chromosome Induced by X-Rays.

Authors:  Yanti Lusiyanti; Mukh Syaifudin; Tuti Budiantari; Sofiati Purnami; Dwi Ramadhani
Journal:  Genome Integr       Date:  2019-07-19

5.  A dose-response curve for biodosimetry from a 6 MV electron linear accelerator.

Authors:  M M P Lemos-Pinto; M Cadena; N Santos; T S Fernandes; E Borges; A Amaral
Journal:  Braz J Med Biol Res       Date:  2015-05-26       Impact factor: 2.590
  5 in total

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