Literature DB >> 7528820

[A preliminary study of HCV infections with hemophilia and their family members].

H Y Sun1, Z X Li, W L Liu, H Z Xu, S H Yang, J Z Tang, L J Hao.   

Abstract

28 cases of hemophilia were examined for HCV infection status by using the Kehua anti-HCV ELISA kit of second generation. It was found that the infection rate was 78.5% and the infection rate was even higher with patients who had received transfusions or preparations of coagulatory factors. 10 families of 15 patients were also investigated. It was found that of 15 hemophilia patients, 12 showed positive anti-HCV, while none of their 53 family members exhibited any positive anti-HCV. In 8 children of 9 couples no positive anti-HCV was found. Our results revealed that the hemophilia patient may get infected with HCV by receiving multiple transfusions or preparation of coagulatory factors. The risk of getting infected with HCV via daily-life contact including sexual contact is extremely low.

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Year:  1994        PMID: 7528820     DOI: 10.1007/bf02886802

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN: 0257-716X


  4 in total

1.  Hepatitis C antibody profile and viraemia prevalence in adults with severe haemophilia.

Authors:  R S Tedder; M Briggs; C Ring; P W Tuke; P Jones; G F Savidge; B Rodgers; J A Garson
Journal:  Br J Haematol       Date:  1991-11       Impact factor: 6.998

2.  Use of several second generation serological assays to determine the true prevalence of hepatitis C virus infection in haemophiliacs treated with non-virus inactivated factor VIII and IX concentrates.

Authors:  H G Watson; C A Ludlam; S Rebus; L Q Zhang; J F Peutherer; P Simmonds
Journal:  Br J Haematol       Date:  1992-04       Impact factor: 6.998

3.  The low risk of hepatitis C virus transmission among sexual partners of hepatitis C-infected hemophilic males: an international, multicenter study.

Authors:  D B Brettler; P M Mannucci; A Gringeri; J E Rasko; A D Forsberg; M G Rumi; R J Garsia; K A Rickard; M Colombo
Journal:  Blood       Date:  1992-07-15       Impact factor: 22.113

4.  Prevalence of anti-HCV antibodies confirmed by recombinant immunoblot in different population subsets in The Netherlands.

Authors:  C L Van der Poel; H W Reesink; E P Mauser-Bunschoten; R H Kaufmann; A Leentvaar-Kuypers; R A Chamuleau; W Schaasberg; E Bakker; P J Exel-Oehlers; I Theobalds
Journal:  Vox Sang       Date:  1991       Impact factor: 2.144

  4 in total

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