Literature DB >> 7527487

Chlorophyll and chlorophyllin as modifiers of genotoxic effects.

D Sarkar1, A Sharma, G Talukder.   

Abstract

Reports on an inverse relationship between the consumption of fresh vegetables and human gastrointestinal cancer have been followed by screening for the protective activity of a large number of plant extracts, including leafy vegetables. Chlorophyll is ubiquitous in all green plant parts. Chlorophyllins are derivatives of chlorophyll in which the central magnesium atom is replaced by other metals, such as cobalt, copper or iron. An attempt has been made in this article to review the relative efficacy of chlorophyll and chlorophyllin in modifying the genotoxic effects of various known toxicants.

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Year:  1994        PMID： 7527487     DOI： 10.1016/0165-1110(94)90017-5

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  6 in total

1.  Screening and identification of compounds with antiviral activity against hepatitis B virus using a safe compound library and novel real-time immune-absorbance PCR-based high throughput system.

Authors:  Jason Lamontagne; Courtney Mills; Richeng Mao; Cally Goddard; Dawei Cai; Haitao Guo; Andy Cuconati; Timothy Block; Xuanyong Lu
Journal:  Antiviral Res       Date:  2013-02-13       Impact factor: 5.970

2.  Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health Study.

Authors:  Yessenia M Tantamango; Synnove F Knutsen; W Lawrence Beeson; Gary Fraser; Joan Sabate
Journal:  Nutr Cancer       Date:  2011       Impact factor: 2.900

3.  Nutrition and cancer: a review of the evidence for an anti-cancer diet.

Authors:  Michael S Donaldson
Journal:  Nutr J       Date:  2004-10-20       Impact factor: 3.271

4.  CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin.

Authors:  Kaarthik John; Rao L Divi; Channa Keshava; Christine C Orozco; Marie E Schockley; Diana L Richardson; Miriam C Poirier; Joginder Nath; Ainsley Weston
Journal:  Cancer Lett       Date:  2010-02-16       Impact factor: 8.679

5.  Antimutagenic effect of dioscorea pentaphylla on genotoxic effect induced by methyl methanesulfonate in the Drosophila wing spot test.

Authors:  G Prakash; B B Hosetti; B L Dhananjaya
Journal:  Toxicol Int       Date:  2014 Sep-Dec

6.  Inhibition of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-mediated DNA-adduct formation by chlorophyllin in Drosophila.

Authors:  C Sugiyama; A Shinoda; H Hayatsu; T Negishi
Journal:  Jpn J Cancer Res       Date:  1996-04
  6 in total

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