Literature DB >> 7527345

Galantide stimulates sexual behaviour in male rats.

A Benelli1, R Arletti, A Bertolini, B Menozzi, R Basaglia, R Poggioli.   

Abstract

While intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. These data further suggest that galanin plays a physiological role in male sexual behavior.

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Year:  1994        PMID: 7527345     DOI: 10.1016/0014-2999(94)90352-2

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  3 in total

Review 1.  Galanin--a neuropeptide with inhibitory actions.

Authors:  K Kask; U Langel; T Bartfai
Journal:  Cell Mol Neurobiol       Date:  1995-12       Impact factor: 5.046

Review 2.  Galanin-acetylcholine interactions in rodent memory tasks and Alzheimer's disease.

Authors:  M P McDonald; J N Crawley
Journal:  J Psychiatry Neurosci       Date:  1997-11       Impact factor: 6.186

3.  Delineation of the peptide binding site of the human galanin receptor.

Authors:  K Kask; M Berthold; U Kahl; G Nordvall; T Bartfai
Journal:  EMBO J       Date:  1996-01-15       Impact factor: 11.598

  3 in total

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