Literature DB >> 7525887

The role of tissue inhibitor of metalloproteinase-1 in specific aspects of cancer progression and reproduction.

R Khokha1, P Waterhouse.   

Abstract

Tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of the multi member family of matrix metalloproteinases (MMPs). Since MMP function is fundamental to events that require tissue remodelling, TIMPs regulate normal biological processes by inhibiting MMPs, and are of importance in pathological conditions. In this chapter we review evidence for the suppressive role of TIMP-1 in the malignant progression of cancer and of its regulatory function in controlling invasion during blastocyst implantation and development.

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Year:  1994        PMID： 7525887     DOI： 10.1007/bf01050418

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  40 in total

Review 1.  Tumor interactions with the vasculature: angiogenesis and tumor metastasis.

Authors:  C H Blood; B R Zetter
Journal:  Biochim Biophys Acta       Date:  1990-06-01

2.  A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor.

Authors:  A Passaniti; R M Taylor; R Pili; Y Guo; P V Long; J A Haney; R R Pauly; D S Grant; G R Martin
Journal:  Lab Invest       Date:  1992-10       Impact factor: 5.662

3.  Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases.

Authors:  O A Alvarez; D F Carmichael; Y A DeClerck
Journal:  J Natl Cancer Inst       Date:  1990-04-04       Impact factor: 13.506

4.  Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts.

Authors:  K J Leco; L J Hayden; R R Sharma; H Rocheleau; A H Greenberg; D R Edwards
Journal:  Gene       Date:  1992-08-15       Impact factor: 3.688

5.  Different patterns of gene expression in ras-resistant and ras-sensitive cells.

Authors:  A B Tuck; S M Wilson; R Khokha; A F Chambers
Journal:  J Natl Cancer Inst       Date:  1991-04-03       Impact factor: 13.506

Review 6.  Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions.

Authors:  D T Denhardt; B Feng; D R Edwards; E T Cocuzzi; U M Malyankar
Journal:  Pharmacol Ther       Date:  1993-09       Impact factor: 12.310

7.  Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription.

Authors:  D R Edwards; H Rocheleau; R R Sharma; A J Wills; A Cowie; J A Hassell; J K Heath
Journal:  Biochim Biophys Acta       Date:  1992-11-15

8.  Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells.

Authors:  R Khokha; M J Zimmer; C H Graham; P K Lala; P Waterhouse
Journal:  J Natl Cancer Inst       Date:  1992-07-01       Impact factor: 13.506

9.  Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

Authors:  D R Edwards; G Murphy; J J Reynolds; S E Whitham; A J Docherty; P Angel; J K Heath
Journal:  EMBO J       Date:  1987-07       Impact factor: 11.598

10.  Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro.

Authors:  C M Alexander; Z Werb
Journal:  J Cell Biol       Date:  1992-08       Impact factor: 10.539
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  5 in total

Review 1.  Matrix metalloproteinase inhibitors.

Authors:  S M Wojtowicz-Praga; R B Dickson; M J Hawkins
Journal:  Invest New Drugs       Date:  1997       Impact factor: 3.850

2.  Transplantation of mesenchymal stem cells expressing TIMP-1-shRNA improves hepatic fibrosis in CCl₄-treated rats.

Authors:  Yingwei Zhu; Zongning Miao; Lei Gong; Weichang Chen
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

3.  Quantitation of TIMP-1 in plasma of healthy blood donors and patients with advanced cancer.

Authors:  M N Holten-Andersen; G Murphy; H J Nielsen; A N Pedersen; I J Christensen; G Høyer-Hansen; N Brünner; R W Stephens
Journal:  Br J Cancer       Date:  1999-05       Impact factor: 7.640

4.  Pair-wise comparison analysis of differential expression of mRNAs in early and advanced stage primary colorectal adenocarcinomas.

Authors:  Tze Pheng Lau; April Camilla Roslani; Lay Hoong Lian; Hwa Chia Chai; Ping Chin Lee; Ida Hilmi; Khean Lee Goh; Kek Heng Chua
Journal:  BMJ Open       Date:  2014-08-08       Impact factor: 2.692

5.  TIMP-1 is a novel serum biomarker for the diagnosis of colorectal cancer: A meta-analysis.

Authors:  Chunyan Meng; Xiaowei Yin; Jingting Liu; Kaifeng Tang; Hongchao Tang; Jianhua Liao
Journal:  PLoS One       Date:  2018-11-20       Impact factor: 3.240
  5 in total

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